| Literature DB >> 18256418 |
Hanitra Rakotonirina1, Céline Barnadas, Rogelin Raherijafy, Hery Andrianantenaina, Arsène Ratsimbasoa, Laurence Randrianasolo, Martial Jahevitra, Valérie Andriantsoanirina, Didier Ménard.
Abstract
The main purpose of this study was to assess the accuracy of various techniques available for diagnosis of malaria. Blood samples were collected from 313 patients with clinical suspicion of uncomplicated malaria in 2 primary health centers in Madagascar. The presence of Plasmodium parasites was assessed by conventional microscopy, 2 rapid diagnostic tests (one HRP2-based test, PALUTOP(+4), and one pLDH-based test, OptiMAL-IT), and real-time polymerase chain reaction (PCR), which is used as the "gold standard" method. The degree of agreement observed was very high for microscopy (0.99) and the HRP2-based test (0.93) and high for the pLDH-based test (0.82). Public-health implications are also discussed in this paper.Entities:
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Year: 2008 PMID: 18256418
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN: 0002-9637 Impact factor: 2.345