| Literature DB >> 18255291 |
Monika Ermann1, Doris Riether, Edward R Walker, Innocent F Mushi, James E Jenkins, Beatriz Noya-Marino, Mark L Brewer, Malcolm G Taylor, Patricia Amouzegh, Stephen P East, Brian W Dymock, Mark J Gemkow, Andreas F Kahrs, Andreas Ebneth, Sabine Löbbe, Kathy O'Shea, Daw-Tsun Shih, David Thomson.
Abstract
A high-throughput screening campaign resulted in the discovery of a highly potent dual cannabinoid receptor 1 (CB1) and 2 (CB2) agonist. Following a thorough SAR exploration, a series of selective CB2 full agonists were identified.Entities:
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Year: 2008 PMID： 18255291 DOI： 10.1016/j.bmcl.2008.01.042
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823