OBJECTIVE: To determine the extent of association and relative risk of developing ocular surface squamous neoplasia (OSSN) among HIV positive patients seen in July 2004 at Sekuru Kaguvi Eye Unit, in Harare, Zimbabwe. DESIGN: Prospective study. SETTING: Sekuru Kaguvi Eye Unit. SUBJECTS: All patients who presented with conjunctival growths in July 2004. MAIN OUTCOME MEASURE: Relative risk. RESULTS: The relative risk of being HIV positive among patients with ocular surface squamous neoplasia was 3.6 with 95% CI 1.5 to 8.6. The mean CD4 cell count level was significantly lower among OSSN patients when compared to patients with non-ocular surface squamous neoplasia. RECOMMENDATIONS: 1. HIV related malignancies can be used as an indicator of when to commence patients on anti-retroviral (ARVs) when CD4 counts are not accessible; 2. Medical practitioners in resource-poor settings should conduct meaningful operational research as part and parcel of their routine clinical work using available resources, since funding is not readily available.
OBJECTIVE: To determine the extent of association and relative risk of developing ocular surface squamous neoplasia (OSSN) among HIV positive patients seen in July 2004 at Sekuru Kaguvi Eye Unit, in Harare, Zimbabwe. DESIGN: Prospective study. SETTING: Sekuru Kaguvi Eye Unit. SUBJECTS: All patients who presented with conjunctival growths in July 2004. MAIN OUTCOME MEASURE: Relative risk. RESULTS: The relative risk of being HIV positive among patients with ocular surface squamous neoplasia was 3.6 with 95% CI 1.5 to 8.6. The mean CD4 cell count level was significantly lower among OSSNpatients when compared to patients with non-ocular surface squamous neoplasia. RECOMMENDATIONS: 1. HIV related malignancies can be used as an indicator of when to commence patients on anti-retroviral (ARVs) when CD4 counts are not accessible; 2. Medical practitioners in resource-poor settings should conduct meaningful operational research as part and parcel of their routine clinical work using available resources, since funding is not readily available.
Authors: Christine A Kiire; Rosalind M K Stewart; Sathish Srinivasan; Heinrich Heimann; Stephen B Kaye; Baljean Dhillon Journal: Eye (Lond) Date: 2018-12-28 Impact factor: 3.775
Authors: Maurits Nc de Koning; Keith Waddell; Joseph Magyezi; Karin Purdie; Charlotte Proby; Catherine Harwood; Sebastian Lucas; Robert Downing; Wim Gv Quint; Robert Newton Journal: Infect Agent Cancer Date: 2008-09-10 Impact factor: 2.965