Literature DB >> 18253813

Zirconium oxide regulates RNA interfering of osteoblast-like cells.

Annalisa Palmieri1, Furio Pezzetti, Giorgio Brunelli, Ilaria Zollino, Lorenzo Lo Muzio, Marcella Martinelli, Luca Scapoli, Marzia Arlotti, Elena Masiero, Francesco Carinci.   

Abstract

Zirconium oxide (ZO) has outstanding mechanical properties, high biocompatibility and high resistance to scratching. Since dental implants are made with ZO and the genetic effects of ZO on osteoblasts are incompletely understood, we used microRNA microarray techniques to investigate the translation process in osteoblasts exposed to ZO. By using miRNA microarrays containing 329 probes designed from Human miRNA sequences, we identified in osteoblast-like cells line (MG-63) cultured on ZO disks several miRNA whose expression was significantly modified. The most notable regulated genes acting on osteoblasts are: NOG, SHOX, IGF1, BMP1 and FGFR1. The data reported below represent the first study on translation regulation in osteoblasts exposed to zirconium and one in which the effect of ZO on bone formation has been detected.

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Year:  2008        PMID： 18253813     DOI： 10.1007/s10856-008-3386-5

Source DB:  PubMed          Journal:  J Mater Sci Mater Med        ISSN： 0957-4530            Impact factor:   3.896


  27 in total

1.  Gene expression data preprocessing.

Authors:  J Herrero; R Díaz-Uriarte; J Dopazo
Journal:  Bioinformatics       Date:  2003-03-22       Impact factor: 6.937

2.  In vitro evaluation of the mutagenic and carcinogenic power of high purity zirconia ceramic.

Authors:  V Covacci; N Bruzzese; G Maccauro; C Andreassi; G A Ricci; C Piconi; E Marmo; W Burger; A Cittadini
Journal:  Biomaterials       Date:  1999-02       Impact factor: 12.479

3.  Effects of Emdogain on osteoblast gene expression.

Authors:  F Carinci; A Piattelli; L Guida; V Perrotti; G Laino; A Oliva; M Annunziata; A Palmieri; F Pezzetti
Journal:  Oral Dis       Date:  2006-05       Impact factor: 3.511

4.  Comparison between freestanding and tooth-connected partially stabilized zirconia implants after two years' function in monkeys: a clinical and histologic study.

Authors:  Y Akagawa; R Hosokawa; Y Sato; K Kamayama
Journal:  J Prosthet Dent       Date:  1998-11       Impact factor: 3.426

5.  Bone morphogenetic protein 1 is an extracellular processing enzyme of the laminin 5 gamma 2 chain.

Authors:  S Amano; I C Scott; K Takahara; M Koch; M F Champliaud; D R Gerecke; D R Keene; D L Hudson; T Nishiyama; S Lee; D S Greenspan; R E Burgeson
Journal:  J Biol Chem       Date:  2000-07-28       Impact factor: 5.157

6.  Initial osteoblast-like cell response to pure titanium and zirconia/alumina ceramics.

Authors:  Hee-Cheol Ko; Jung-Suk Han; Maria Bächle; Jun-Hyeog Jang; Sang-Wan Shin; Dae-Joon Kim
Journal:  Dent Mater       Date:  2007-01-02       Impact factor: 5.304

7.  Interface histology of unloaded and early loaded partially stabilized zirconia endosseous implant in initial bone healing.

Authors:  Y Akagawa; Y Ichikawa; H Nikai; H Tsuru
Journal:  J Prosthet Dent       Date:  1993-06       Impact factor: 3.426

8.  Heterozygous mutations in the gene encoding noggin affect human joint morphogenesis.

Authors:  Y Gong; D Krakow; J Marcelino; D Wilkin; D Chitayat; R Babul-Hirji; L Hudgins; C W Cremers; F P Cremers; H G Brunner; K Reinker; D L Rimoin; D H Cohn; F R Goodman; W Reardon; M Patton; C A Francomano; M L Warman
Journal:  Nat Genet       Date:  1999-03       Impact factor: 38.330

9.  Biological glass coating on ceramic materials: in vitro evaluation using primary osteoblast cultures from healthy and osteopenic rat bone.

Authors:  P Torricelli; E Verné; C V Brovarone; P Appendino; F Rustichelli; A Krajewski; A Ravaglioli; G Pierini; M Fini; G Giavaresi; R Giardino
Journal:  Biomaterials       Date:  2001-09       Impact factor: 12.479

Review 10.  Zirconia as a ceramic biomaterial.

Authors:  C Piconi; G Maccauro
Journal:  Biomaterials       Date:  1999-01       Impact factor: 12.479
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  6 in total

Review 1.  Global gene expression analysis for evaluation and design of biomaterials.

Authors:  Nobutaka Hanagata; Taro Takemura; Takashi Minowa
Journal:  Sci Technol Adv Mater       Date:  2010-02-22       Impact factor: 8.090

Review 2.  Molecular genetic studies of gene identification for osteoporosis: the 2009 update.

Authors:  Xiang-Hong Xu; Shan-Shan Dong; Yan Guo; Tie-Lin Yang; Shu-Feng Lei; Christopher J Papasian; Ming Zhao; Hong-Wen Deng
Journal:  Endocr Rev       Date:  2010-03-31       Impact factor: 19.871

3.  Biocompatibility of ZrO2 vs. Y-TZP Alloys: Influence of Their Composition and Surface Topography.

Authors:  Alex Tchinda; Laëtitia Chézeau; Gaël Pierson; Richard Kouitat-Njiwa; B H Rihn; Pierre Bravetti
Journal:  Materials (Basel)       Date:  2022-07-01       Impact factor: 3.748

4.  Compressive Strength and Setting Time of MTA and Portland Cement Associated with Different Radiopacifying Agents.

Authors:  Mario Tanomaru-Filho; Vanessa Morales; Guilherme F da Silva; Roberta Bosso; José M S N Reis; Marco A H Duarte; Juliane M Guerreiro-Tanomaru
Journal:  ISRN Dent       Date:  2012-08-23

5.  Behavior of osteoblastic cells cultured on titanium and structured zirconia surfaces.

Authors:  Rita Depprich; Michelle Ommerborn; Holger Zipprich; Christian Naujoks; Jörg Handschel; Hans-Peter Wiesmann; Norbert R Kübler; Ulrich Meyer
Journal:  Head Face Med       Date:  2008-12-08       Impact factor: 2.151

6.  Titanium and Zirconium Levels Are Associated with Changes in MicroRNAs Expression: Results from a Human Cross-Sectional Study on Obese Population.

Authors:  Gianguido Cossellu; Valeria Motta; Laura Dioni; Laura Angelici; Luisella Vigna; Giampietro Farronato; Angela Cecilia Pesatori; Valentina Bollati
Journal:  PLoS One       Date:  2016-09-09       Impact factor: 3.240
  6 in total

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