| Literature DB >> 18251547 |
Yasunao Hattori1, Shin-ichi Furuhata, Motonori Okajima, Hiroyuki Konno, Masato Abe, Hideto Miyoshi, Tetsuhisa Goto, Hidefumi Makabe.
Abstract
Total synthesis of pyranicin was achieved using Cl2Pd(CH3CN)2-catalyzed diastereoselective cyclization of the allylic ester as the key step. The inhibitory activity of this compound for mitochondrial NADH-ubiquinone oxidoreductase (complex I) was slightly poorer than that of ordinary mono-THF acetogenins such as cis-solamin.Entities:
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Year: 2008 PMID： 18251547 DOI： 10.1021/ol702902w
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005