Literature DB >> 18251338

Determinants of hormone therapy discontinuation among female veterans nationally.

Sally G Haskell1, Bevanne Bean-Mayberry, Joseph L Goulet, Melissa Skanderson, Chester B Good, Amy C Justice.   

Abstract

PURPOSE: The growing presence of female veterans within the Department of Veterans Affairs (VA) health care system highlights the need to assess the quality of and access to gender-specific care for menopause. We assessed the use of hormone therapy (HT) among female veterans before and after the release of the Women's Health Initiative clinical trial results and evaluated whether the structure of women's health care services within the VA system affects the use of HT.
METHODS: We identified all female veterans using HT in 2001 by using the VA pharmacy benefits management database and administrative data. Subjects identified as using HT in 2001 were evaluated to determine estrogen use status in 2003 and 2004. We calculated the change in HT use over time and performed multivariate analyses to identify patient and utilization determinants of HT discontinuation.
RESULTS: In 2001, 36,222 female veterans used HT. By 2004, 23,924 (66%) had discontinued HT. Subjects who had used a VA women's clinic or were younger (40-54 years of age) were significantly less likely to discontinue HT. However, Hispanic ethnicity, African American race, and clinical diagnoses such as heart disease and mastectomy were significantly associated with discontinuation.
CONCLUSION: Discontinuation rates in the VA system parallel those in the private sector. However, patients with any use of VA women's clinics were less likely to discontinue HT, indicating a practice setting variation that may indicate either more specific care or differential implementation of the new HT guidelines. Further research is warranted to assess whether a disparity occurs according to practice setting (or provider factors) with rapid shifts in guidelines.

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Mesh:

Year:  2008        PMID: 18251338      PMCID: PMC3115618          DOI: 10.7205/milmed.173.1.91

Source DB:  PubMed          Journal:  Mil Med        ISSN: 0026-4075            Impact factor:   1.437


  20 in total

Review 1.  Hormone therapy to prevent disease and prolong life in postmenopausal women.

Authors:  D Grady; S M Rubin; D B Petitti; C S Fox; D Black; B Ettinger; V L Ernster; S R Cummings
Journal:  Ann Intern Med       Date:  1992-12-15       Impact factor: 25.391

2.  Brief report: attitudes toward hormone therapy after the Women's Health Initiative: a comparison of internists and gynecologists.

Authors:  Allan S Brett; Patricia I Carney; Robert E McKeown
Journal:  J Gen Intern Med       Date:  2005-05       Impact factor: 5.128

3.  The impact of clinical trials on the use of hormone replacement therapy. A population-based study.

Authors:  Nancy Kim; Cary Gross; Jeptha Curtis; Glen Stettin; Stephen Wogen; Nami Choe; Harlan M Krumholz
Journal:  J Gen Intern Med       Date:  2005-11       Impact factor: 5.128

4.  Ovarian aging and hormone replacement therapy. Hormonal levels, symptoms, and attitudes of African-American and white women.

Authors:  K T Pham; J A Grisso; E W Freeman
Journal:  J Gen Intern Med       Date:  1997-04       Impact factor: 5.128

5.  Regional variation in the use of medications by older Canadians--a persistent and incompletely understood phenomena.

Authors:  D B Hogan; C J Maxwell; T S Fung; E M Ebly
Journal:  Pharmacoepidemiol Drug Saf       Date:  2003 Oct-Nov       Impact factor: 2.890

6.  Effect of the Women's Health Initiative on women's decisions to discontinue postmenopausal hormone therapy.

Authors:  Bruce Ettinger; Deborah Grady; Anna N A Tosteson; Alice Pressman; Judith L Macer
Journal:  Obstet Gynecol       Date:  2003-12       Impact factor: 7.661

7.  Changes in the use of postmenopausal hormone therapy after the publication of clinical trial results.

Authors:  Jennifer S Haas; Celia P Kaplan; Eric P Gerstenberger; Karla Kerlikowske
Journal:  Ann Intern Med       Date:  2004-02-03       Impact factor: 25.391

8.  Depression and its influence on reproductive endocrine and menstrual cycle markers associated with perimenopause: the Harvard Study of Moods and Cycles.

Authors:  Bernard L Harlow; Lauren A Wise; Michael W Otto; Claudio N Soares; Lee S Cohen
Journal:  Arch Gen Psychiatry       Date:  2003-01

9.  Hormones and menopausal status as predictors of depression in women in transition to menopause.

Authors:  Ellen W Freeman; Mary D Sammel; Li Liu; Clarisa R Gracia; Deborah B Nelson; Lori Hollander
Journal:  Arch Gen Psychiatry       Date:  2004-01

10.  National use of postmenopausal hormone therapy: annual trends and response to recent evidence.

Authors:  Adam L Hersh; Marcia L Stefanick; Randall S Stafford
Journal:  JAMA       Date:  2004-01-07       Impact factor: 56.272

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  6 in total

1.  Menopausal hormone therapy trends before versus after 2002: impact of the Women's Health Initiative Study Results.

Authors:  Sybil L Crawford; Carolyn J Crandall; Carol A Derby; Samar R El Khoudary; L Elaine Waetjen; Mary Fischer; Hadine Joffe
Journal:  Menopause       Date:  2018-12-21       Impact factor: 2.953

2.  Hormone therapy use in women veterans accessing veterans health administration care: a national cross-sectional study.

Authors:  Megan R Gerber; Matthew W King; Suzanne L Pineles; Shannon Wiltsey-Stirman; Bevanne Bean-Mayberry; Sandra J Japuntich; Sally G Haskell
Journal:  J Gen Intern Med       Date:  2014-11-06       Impact factor: 5.128

3.  Reproductive Health of Women Veterans: A Systematic Review of the Literature from 2008 to 2017.

Authors:  Jodie G Katon; Laurie Zephyrin; Anne Meoli; Avanthi Hulugalle; Jeane Bosch; Lisa Callegari; Ileana V Galvan; Kristen E Gray; Kristin O Haeger; Claire Hoffmire; Silvina Levis; Erica W Ma; Jennifer E Mccabe; Yael I Nillni; Suzanne L Pineles; Shivani M Reddy; David A Savitz; Jonathan G Shaw; Elizabeth W Patton
Journal:  Semin Reprod Med       Date:  2019-04-19       Impact factor: 1.303

Review 4.  Postmenopausal hormone therapy is not associated with risk of all-cause dementia and Alzheimer's disease.

Authors:  Jacqueline O'Brien; John W Jackson; Francine Grodstein; Deborah Blacker; Jennifer Weuve
Journal:  Epidemiol Rev       Date:  2013-09-15       Impact factor: 6.222

Review 5.  An Evidence Map of the Women Veterans' Health Research Literature (2008-2015).

Authors:  Elisheva R Danan; Erin E Krebs; Kristine Ensrud; Eva Koeller; Roderick MacDonald; Tina Velasquez; Nancy Greer; Timothy J Wilt
Journal:  J Gen Intern Med       Date:  2017-09-14       Impact factor: 5.128

6.  Predictors and Outcomes Associated With Adherence to Weekly Alendronate in US Military Veterans: Clinical Research Study.

Authors:  Sarah Bou Malham; Benjamin Bowe; Sumon K Sen; Rong Mei Zhang; Barbara Sterkel; Julia P Dunn
Journal:  J Prim Care Community Health       Date:  2019 Jan-Dec
  6 in total

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