Literature DB >> 18251161

Laparoscopic radiofrequency ablation of unresectable hepatic malignancies: indication, limitation and results.

Philipp Hildebrand1, Markus Kleemann, Uwe Roblick, Lutz Mirow, Matthias Birth, Hans-Peter Bruch.   

Abstract

BACKGROUND/AIMS: Radiofrequency-ablation (RFA) is an effective therapeutic option for destruction of irresectable primary and secondary liver tumors and has been successfully performed transcutaneously using sonographic or computer tomographic guidance or by laparotomy. The laparoscopic approach combines a minimal invasiveness with optimal diagnosis.
METHODOLOGY: Between 02/2003 and 10/2005, 14 patients with a total of 45 unresectable liver tumors were treated with laparoscopic radiofrequency-ablation in our hospital. Laparoscopic RFA was primarily performed in patients' superficial lesions adjacent to neighboring organs that could be displaced by laparoscopic maneuvers, deep-sited lesions with a very difficult or impossible percutaneous approach and in combination with other laparoscopic operations.
RESULTS: All intrahepatic tumors could be detected safely by laparoscopic intraoperative ultrasound. Additional liver lesions were identified in 5 (35.7%) of the 14 patients. All 45 tumors of the 14 patients were able to be completely ablated. Laparoscopic RFA yielded no mortality and only one case of postoperative bleeding. During a mean follow-up period of 23.2 months one patient locally recurred, three patients had new malignant nodules and two patients died with disease.
CONCLUSIONS: Laparoscopic RFA is safe and provides a minimally invasive procedure with the option of simultaneous inflow-occlusion during thermoablation. Even more, neighboring organs can be protected, simultaneous resections can be performed and intraoperative ultrasound is used to gain further diagnosis.

Entities:  

Mesh:

Year:  2007        PMID: 18251161

Source DB:  PubMed          Journal:  Hepatogastroenterology        ISSN: 0172-6390


  7 in total

1.  [Clinical application of laparoscopy-assisted and percutaneous radiofrequency ablation for hepatocellular carcinoma].

Authors:  Shude Chen; Hongguang Wang; Wenzhi Zhang; Jiye Chen; Peng Lu
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2018-08-30

2.  Other non-surgical treatments for liver cancer.

Authors:  Paul Revel-Mouroz; Philippe Otal; Marion Jaffro; Antoine Petermann; Olivier Meyrignac; Pierre Rabinel; Fatima-Zohra Mokrane
Journal:  Rep Pract Oncol Radiother       Date:  2017-04-14

3.  [Current state of laparoscopic hepatic surgery: results of a survey of DGAV-members].

Authors:  M Kleemann; A Kühling; P Hildebrand; R Czymek; S Limmer; H Wolken; U Roblick; H P Bruch; C Bürk
Journal:  Chirurg       Date:  2010-12       Impact factor: 0.955

4.  Combined surgical resection and radiofrequency ablation as treatment for metastatic ocular melanoma.

Authors:  Elika Derek; Lea Matsuoka; Sophoclis Alexopoulos; Alexander Fedenko; Yuri Genyk; Rick Selby
Journal:  Surg Today       Date:  2012-07-06       Impact factor: 2.549

5.  Radiofrequency ablation of liver tumors: Actual limitations and potential solutions in the future.

Authors:  Beat M Künzli; Paolo Abitabile; Christoph A Maurer
Journal:  World J Hepatol       Date:  2011-01-27

6.  Radiofrequency ablation of hepatocellular carcinoma: a literature review.

Authors:  Yasunori Minami; Masatoshi Kudo
Journal:  Int J Hepatol       Date:  2011-05-11

7.  Early experience with laparoscopic treatment of liver tumors using a separable cluster electrode with a no-touch technique.

Authors:  Hyun Pyo Hong; Jee Youn Lee; Mi Yeon Lee; Kyung Uk Jung; Byung Ik Kim; Byung Ho Son; Jun Ho Shin; Sung Ryol Lee
Journal:  Wideochir Inne Tech Maloinwazyjne       Date:  2020-05-10       Impact factor: 1.195

  7 in total

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