Successful pregnancy in a patient with Landesman's Group C autosomal dominant polycystic kidney disease.

BACKGROUND: A female with autosomal dominant polycystic kidney disease was followed up over the course of four pregnancies. Her first three pregnancies were unsuccessful. Her fourth pregnancy resulted in a live birth, but at what expense? INVESTIGATIONS: The diagnosis of autosomal dominant polycystic kidney disease was confirmed by ultrasound imaging. Physical examination, blood pressure measurement, and urine and blood analyses were performed at each follow-up visit. DIAGNOSIS: Deterioration of renal function following multiple complicated pregnancies. MANAGEMENT: Attention to blood pressure and proteinuria delayed initiation of dialysis, but effects of the number of pregnancies took their toll. The patient was started on hemodialysis and underwent renal transplantation.