OBJECTIVE: To examine changes in blood flow in the corpus luteum throughout the luteal phase and during early pregnancy. DESIGN: Longitudinal and cross-sectional prospective studies. SETTING: University hospital and city general hospital. PATIENT(S): Sixty-one women with normal menstrual cycles and normal luteal function, 13 women with hCG-induced ovulatory cycle, 10 women with luteal phase defect, six women with luteinized unruptured follicle (LUF), and 17 pregnant women (4-10 weeks of gestation). INTERVENTION(S): Blood-flow impedance in the corpus luteum was assessed by transvaginal color-pulsed Doppler ultrasound. MAIN OUTCOME MEASURES: Resistance index (RI) in the corpus luteum. RESULT(S): In the normal menstrual cycle, the RI of the preovulatory follicle was high and significantly decreased after ovulation. Luteal-RI further decreased during the early to midluteal phase but significantly increased during the late luteal phase. Those changes in luteal-RI were similar to those of the hCG-induced ovulatory cycle. Luteal-RI during the midluteal phase was significantly higher in the patients with luteal phase defect than in women with normal luteal function. Luteal-RI of the LUF patients remained high throughout the luteal phase. In pregnant women, luteal-RI remained at the midluteal phase level until 7 weeks of gestation and significantly increased thereafter. CONCLUSION(S): The change in luteal-RI was associated with corpus luteum development and corpus luteum regression. Luteal-RI was closely associated with luteal function.
OBJECTIVE: To examine changes in blood flow in the corpus luteum throughout the luteal phase and during early pregnancy. DESIGN: Longitudinal and cross-sectional prospective studies. SETTING: University hospital and city general hospital. PATIENT(S): Sixty-one women with normal menstrual cycles and normal luteal function, 13 women with hCG-induced ovulatory cycle, 10 women with luteal phase defect, six women with luteinized unruptured follicle (LUF), and 17 pregnant women (4-10 weeks of gestation). INTERVENTION(S): Blood-flow impedance in the corpus luteum was assessed by transvaginal color-pulsed Doppler ultrasound. MAIN OUTCOME MEASURES: Resistance index (RI) in the corpus luteum. RESULT(S): In the normal menstrual cycle, the RI of the preovulatory follicle was high and significantly decreased after ovulation. Luteal-RI further decreased during the early to midluteal phase but significantly increased during the late luteal phase. Those changes in luteal-RI were similar to those of the hCG-induced ovulatory cycle. Luteal-RI during the midluteal phase was significantly higher in the patients with luteal phase defect than in women with normal luteal function. Luteal-RI of the LUF patients remained high throughout the luteal phase. In pregnant women, luteal-RI remained at the midluteal phase level until 7 weeks of gestation and significantly increased thereafter. CONCLUSION(S): The change in luteal-RI was associated with corpus luteum development and corpus luteum regression. Luteal-RI was closely associated with luteal function.
Authors: C Gómez-Seco; B Alegre; F Martínez-Pastor; J G Prieto; J R González-Montaña; M E Alonso; J C Domínguez Journal: Vet Res Commun Date: 2017-03-23 Impact factor: 2.459
Authors: Cecily V Bishop; Theodore A Molskness; Fuhua Xu; J Todd Belcik; Jonathan R Lindner; Ov D Slayden; Richard L Stouffer Journal: J Med Primatol Date: 2014-06-20 Impact factor: 0.667
Authors: Gernot Faustmann; Andreas Meinitzer; Christoph Magnes; Beate Tiran; Barbara Obermayer-Pietsch; Hans-Jürgen Gruber; Josep Ribalta; Edmond Rock; Johannes M Roob; Brigitte M Winklhofer-Roob Journal: PLoS One Date: 2018-07-10 Impact factor: 3.240