Literature DB >> 18249311

Limitations of the QuantiFERON-TB Gold test in detecting Mycobacterium tuberculosis infection in immunocompromised patients.

Mads Hornum1, Klaus Leth Mortensen, Anne-Lise Kamper, Ase Bengård Andersen.   

Abstract

Four cases are presented, immunosuppressed by at least three different mechanisms: one HIV-positive patient with a CD4 count of 0.29 x 10(6)/ml, one malnourished patient, and two kidney-transplanted patients. All patients had a negative interferon (IFN)-gamma test for suspected tuberculosis (TB), but a positive culture. We conclude that a negative IFN-gamma test does not exclude TB disease in immunosuppressed patients.

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Year:  2007        PMID: 18249311     DOI: 10.1016/j.ejim.2007.03.020

Source DB:  PubMed          Journal:  Eur J Intern Med        ISSN: 0953-6205            Impact factor:   4.487


  4 in total

1.  Latent infection screening and prevalence in cancer patients born outside of Australia: a universal versus risk-based approach?

Authors:  Gemma Reynolds; Gabrielle Haeusler; Monica A Slavin; Benjamin Teh; Karin Thursky
Journal:  Support Care Cancer       Date:  2021-03-24       Impact factor: 3.603

2.  Tuberculosis dissemination in kidney transplant recipient treated with anti-CD40 monoclonal antibody: a case report.

Authors:  Kamila Bednarova; Janka Slatinska; Ondrej Fabian; Pavel Wohl; Emilia Kopecka; Ondrej Viklicky
Journal:  BMC Nephrol       Date:  2022-08-19       Impact factor: 2.585

3.  Vitamin D status contributes to the antimicrobial activity of macrophages against Mycobacterium leprae.

Authors:  Elliot W Kim; Rosane M B Teles; Salem Haile; Philip T Liu; Robert L Modlin
Journal:  PLoS Negl Trop Dis       Date:  2018-07-02

4.  Use of T Cell Mediated Immune Functional Assays for Adjustment of Immunosuppressive or Anti-infective Agents in Solid Organ Transplant Recipients: A Systematic Review.

Authors:  Omid Rezahosseini; Dina Leth Møller; Andreas Dehlbæk Knudsen; Søren Schwartz Sørensen; Michael Perch; Finn Gustafsson; Allan Rasmussen; Sisse Rye Ostrowski; Susanne Dam Nielsen
Journal:  Front Immunol       Date:  2020-10-15       Impact factor: 7.561

  4 in total

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