Literature DB >> 18249285

Botulinum toxin type A (Botox) for the neuromuscular correction of excessive gingival display on smiling (gummy smile).

Mario Polo1.   

Abstract

INTRODUCTION: Previously, botulinum toxin type A (BTX-A) (Botox; Allergan, Irvine, Calif) was shown to be effective in reducing excessive gingival display in 5 patients with gummy smiles. This study was conducted to determine whether the doses and the primary injection sites used in the pilot study for the correction of gummy smiles provide consistent, statistically significant, and esthetically pleasing results.
METHODS: Thirty patients received BTX-A injections to reduce excessive gingival display. Gingival display was defined as the difference between the lower margin of the upper lip and the superior margin of the right incisor. Patients were followed at 2, 4, 8, 12, 16, 20, and 24 weeks postinjection, with changes documented by photographs and videos. At week 2, the patients rated the effects of BTX-A. A group of specialty clinicians also evaluated the effects of BTX-A.
RESULTS: Preinjection gingival display averaged 5.2 +/- 1.4 mm in the 30 patients. At 2 weeks postinjection, mean gingival display had declined to 0.09 mm (+/- 1.06 mm) in 30 patients (t = 26.01, P <.00001). The average lip-drop at 2 weeks was 5.1 mm for 30 patients. Gingival display gradually increased from 2 weeks postinjection through 24 weeks, but, at 24 weeks, average gingival display had not returned to baseline values. Based on predictions from a third-order polynomial equation, the baseline average of 5.2 mm would not be reached until 30 to 32 weeks postinjection. Patients and specialty evaluators rated the effects of BTX-A as highly favorable.
CONCLUSIONS: BTX-A injections for the neuromuscular correction of gummy smiles caused by hyperfunctional upper lip elevator muscles was effective and statistically superior to baseline smiles, although the effect is transitory.

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Year:  2008        PMID: 18249285     DOI: 10.1016/j.ajodo.2007.04.033

Source DB:  PubMed          Journal:  Am J Orthod Dentofacial Orthop        ISSN: 0889-5406            Impact factor:   2.650


  28 in total

1.  Neurotransmitter vesicle release from human model neurons (NT2) is sensitive to botulinum toxin A.

Authors:  Million Adane Tegenge; Helge Böhnel; Frank Gessler; Gerd Bicker
Journal:  Cell Mol Neurobiol       Date:  2012-02-29       Impact factor: 5.046

2.  Management of gummy smile with Botulinum Toxin Type-A: A case report.

Authors:  Sudeeptha Dinker; A Anitha; Abhinay Sorake; Kishore Kumar
Journal:  J Int Oral Health       Date:  2014-02-26

3.  Effects of different doses of abobotulinumtoxinA for the treatment of anterior gingival smile.

Authors:  Doris Hexsel; Taciana Dal'Forno; Fernanda Camozzato; Indira Valente; Mariana Soirefmann; Aline Flor Silva; Carolina Siega
Journal:  Arch Dermatol Res       Date:  2020-07-28       Impact factor: 3.017

Review 4.  Clinical uses of botulinum toxin A in smile aesthetic modification.

Authors:  S N Delpachitra; A W Sklavos; M Dastaran
Journal:  Br Dent J       Date:  2018-09-28       Impact factor: 1.626

5.  Botox as an adjunct to orthognathic surgery for a case of severe vertical maxillary excess.

Authors:  Adarsh S Indra; P P Biswas; V T Vineet; T Yeshaswini
Journal:  J Maxillofac Oral Surg       Date:  2011-02-25

6.  Lip repositioning, an alternative treatment of gummy smile - A case report.

Authors:  Deepthi K; Umesh Yadalam; Rajeev Ranjan; Sarita Joshi Narayan
Journal:  J Oral Biol Craniofac Res       Date:  2017-09-27

7.  Orthodontist's Role in Orthognathic Surgery.

Authors:  John O Wirthlin; Pradip R Shetye
Journal:  Semin Plast Surg       Date:  2013-08       Impact factor: 2.314

8.  Diagnosing and treatment planning inadequate tooth display.

Authors:  F Spear
Journal:  Br Dent J       Date:  2016-10-21       Impact factor: 1.626

9.  Botulinum Toxin-A in the Treatment of Excessive Gingival Display: A Clinical Study.

Authors:  B Anton Tyrone Soris; K Vandana Shenoy; Ashok Ramadorai; C S C Satish Kumar; Laavanya Marimuthu
Journal:  J Maxillofac Oral Surg       Date:  2021-03-15

10.  A successful management of sever gummy smile using gingivectomy and botulinum toxin injection: A case report.

Authors:  Diana Mostafa
Journal:  Int J Surg Case Rep       Date:  2017-12-01
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