Literature DB >> 1824787

Sindbis virus nsP1 functions in negative-strand RNA synthesis.

Y F Wang1, S G Sawicki, D L Sawicki.   

Abstract

A mutation at nucleotide 1101 of Sindbis virus ts11 nsP1 caused temperature-sensitive negative-strand synthesis and suppressed the 24R phenotype, which is caused by a mutation in nsP4. Nonstructural proteins synthesized and accumulated by ts11 at 40 degrees C did not cause the reactivation of negative-strand synthesis upon return to 30 degrees C and did not prevent the formation of new replication complexes at 30 degrees C.

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Year:  1991        PMID： 1824787      PMCID： PMC239844     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  15 in total

1.  Synthesis and processing of the nonstructural polyproteins of several temperature-sensitive mutants of Sindbis virus.

Authors:  W R Hardy; Y S Hahn; R J de Groot; E G Strauss; J H Strauss
Journal:  Virology       Date:  1990-07       Impact factor: 3.616

2.  Processing the nonstructural polyproteins of Sindbis virus: study of the kinetics in vivo by using monospecific antibodies.

Authors:  W R Hardy; J H Strauss
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

3.  Mapping of RNA- temperature-sensitive mutants of Sindbis virus: assignment of complementation groups A, B, and G to nonstructural proteins.

Authors:  Y S Hahn; E G Strauss; J H Strauss
Journal:  J Virol       Date:  1989-07       Impact factor: 5.103

4.  Production of infectious RNA transcripts from Sindbis virus cDNA clones: mapping of lethal mutations, rescue of a temperature-sensitive marker, and in vitro mutagenesis to generate defined mutants.

Authors:  C M Rice; R Levis; J H Strauss; H V Huang
Journal:  J Virol       Date:  1987-12       Impact factor: 5.103

5.  Deletion mapping of Sindbis virus DI RNAs derived from cDNAs defines the sequences essential for replication and packaging.

Authors:  R Levis; B G Weiss; M Tsiang; H Huang; S Schlesinger
Journal:  Cell       Date:  1986-01-17       Impact factor: 41.582

6.  Temperature sensitive shut-off of alphavirus minus strand RNA synthesis maps to a nonstructural protein, nsP4.

Authors:  D Sawicki; D B Barkhimer; S G Sawicki; C M Rice; S Schlesinger
Journal:  Virology       Date:  1990-01       Impact factor: 3.616

7.  Cleavage-site preferences of Sindbis virus polyproteins containing the non-structural proteinase. Evidence for temporal regulation of polyprotein processing in vivo.

Authors:  R J de Groot; W R Hardy; Y Shirako; J H Strauss
Journal:  EMBO J       Date:  1990-08       Impact factor: 11.598

8.  The effect of loss of regulation of minus-strand RNA synthesis on Sindbis virus replication.

Authors:  S G Sawicki; D L Sawicki
Journal:  Virology       Date:  1986-06       Impact factor: 3.616

9.  Evidence that Sindbis virus NSP2 is an autoprotease which processes the virus nonstructural polyprotein.

Authors:  M X Ding; M J Schlesinger
Journal:  Virology       Date:  1989-07       Impact factor: 3.616

10.  Processing the nonstructural polyproteins of sindbis virus: nonstructural proteinase is in the C-terminal half of nsP2 and functions both in cis and in trans.

Authors:  W R Hardy; J H Strauss
Journal:  J Virol       Date:  1989-11       Impact factor: 5.103
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  45 in total

1.  Engineered viruses to select genes encoding secreted and membrane-bound proteins in mammalian cells.

Authors:  Pierre Moffatt; Patrick Salois; Marie-Hélène Gaumond; Natalie St-Amant; Eric Godin; Christian Lanctôt
Journal:  Nucleic Acids Res       Date:  2002-10-01       Impact factor: 16.971

2.  mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral Research.

Authors:  Changqing Li; Jaime Guillén; Nadia Rabah; Alexandre Blanjoie; Françoise Debart; Jean-Jacques Vasseur; Bruno Canard; Etienne Decroly; Bruno Coutard
Journal:  J Virol       Date:  2015-06-03       Impact factor: 5.103

3.  A novel viral RNA species in Sindbis virus-infected cells.

Authors:  M M Wielgosz; H V Huang
Journal:  J Virol       Date:  1997-12       Impact factor: 5.103

4.  Effects of an opal termination codon preceding the nsP4 gene sequence in the O'Nyong-Nyong virus genome on Anopheles gambiae infectivity.

Authors:  Kevin M Myles; Cindy L H Kelly; Jeremy P Ledermann; Ann M Powers
Journal:  J Virol       Date:  2006-05       Impact factor: 5.103

5.  Alphavirus minus-strand RNA synthesis: identification of a role for Arg183 of the nsP4 polymerase.

Authors:  Cori L Fata; Stanley G Sawicki; Dorothea L Sawicki
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

6.  Modification of Asn374 of nsP1 suppresses a Sindbis virus nsP4 minus-strand polymerase mutant.

Authors:  Cori L Fata; Stanley G Sawicki; Dorothea L Sawicki
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

Review 7.  The alphaviruses: gene expression, replication, and evolution.

Authors:  J H Strauss; E G Strauss
Journal:  Microbiol Rev       Date:  1994-09

8.  Changes in cellular mRNA stability, splicing, and polyadenylation through HuR protein sequestration by a cytoplasmic RNA virus.

Authors:  Michael D Barnhart; Stephanie L Moon; Alexander W Emch; Carol J Wilusz; Jeffrey Wilusz
Journal:  Cell Rep       Date:  2013-11-07       Impact factor: 9.423

9.  Solubilization and immunoprecipitation of alphavirus replication complexes.

Authors:  D J Barton; S G Sawicki; D L Sawicki
Journal:  J Virol       Date:  1991-03       Impact factor: 5.103

10.  Completion of Kunjin virus RNA sequence and recovery of an infectious RNA transcribed from stably cloned full-length cDNA.

Authors:  A A Khromykh; E G Westaway
Journal:  J Virol       Date:  1994-07       Impact factor: 5.103
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