Literature DB >> 18245703

Is treatment of acute type A aortic dissection in septuagenarians justifiable?

Malakh Shrestha1, Nawid Khaladj, Axel Haverich, Christian Hagl.   

Abstract

This study was undertaken to analyze the risk of mortality and neurological complications after treatment of acute type A aortic dissection in septuagenarians. From 1996 through 2002, 24 patients > 70 years underwent surgery for acute type A aortic dissection. Their median age was 75 years (range, 71-82 years), and 15 were male. Eleven (46%) had previous neurological events, 22% presented with hemodynamic instability and aortic rupture was found in 7%. Ten had hypothermic circulatory arrest alone, 3 had it in combination with retrograde cerebral perfusion and 11 had selective antegrade cerebral perfusion as an adjunct. The overall survival rate was 71% (17/24). Temporary neurological dysfunction was found in 3 (12.5%), and permanent neurological dysfunction in 9 (37.5%), leading to death in 3. Comparison of mortality rates and neurological outcome showed a marked tendency towards better outcome in patients who had hypothermic circulatory arrest and selective antegrade cerebral perfusion. Surgery for aortic dissections in the elderly can be performed with acceptable mortality, but there is a high rate of neurological complications. Despite the small number of patients, selective antegrade cerebral perfusion seemed to reduce the incidence of neurological events.

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Year:  2008        PMID: 18245703     DOI: 10.1177/021849230801600109

Source DB:  PubMed          Journal:  Asian Cardiovasc Thorac Ann        ISSN: 0218-4923


  5 in total

1.  Long-term results after aortic valve-sparing operation (David I).

Authors:  Malakh Shrestha; Hassina Baraki; Ilona Maeding; Sebastian Fitzner; Samir Sarikouch; Nawid Khaladj; Christian Hagl; Axel Haverich
Journal:  Eur J Cardiothorac Surg       Date:  2012-01       Impact factor: 4.191

Review 2.  Emergent aortic surgery in octogenarians: is the advanced age a contraindication?

Authors:  Mario Castaño; Javier Gualis; Jose M Martínez-Comendador; Elio Martín; Pasquale Maiorano; Laura Castillo
Journal:  J Thorac Dis       Date:  2017-05       Impact factor: 2.895

3.  Differential aspects of the disease and treatment of Thoracic Acute Aortic Dissection (TAAD)-the European experience.

Authors:  John Pepper
Journal:  Ann Cardiothorac Surg       Date:  2016-07

4.  Outcomes in the current surgical era following operative repair of acute Type A aortic dissection in the elderly: a single-institutional experience.

Authors:  Ahmet Kilic; Richard Tang; Bryan A Whitson; John H Sirak; Chittoor B Sai-Sudhakar; Juan Crestanello; Robert S D Higgins
Journal:  Interact Cardiovasc Thorac Surg       Date:  2013-04-05

5.  Aortic root surgery in septuagenarians: impact of different surgical techniques.

Authors:  Nawid Khaladj; Rainer Leyh; Malakh Shrestha; Sven Peterss; Axel Haverich; Christian Hagl
Journal:  J Cardiothorac Surg       Date:  2009-04-21       Impact factor: 1.637

  5 in total

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