Literature DB >> 18243110

Linking differential chromatin loops to transcriptional decisions.

Effie Apostolou1, Dimitris Thanos.   

Abstract

GATA-1 and GATA-2 control proliferation and differentiation of hematopoietic progenitor cells via transcriptional regulation. In this issue of Molecular Cell, Jing et al. (2008) demonstrate that GATA factor exchange on the Kit locus directs a transcriptional switch by reconfiguring chromatin loops.

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Year:  2008        PMID: 18243110     DOI: 10.1016/j.molcel.2008.01.008

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  2 in total

1.  CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus.

Authors:  Masayuki Sekimata; Mercedes Pérez-Melgosa; Sara A Miller; Amy S Weinmann; Peter J Sabo; Richard Sandstrom; Michael O Dorschner; John A Stamatoyannopoulos; Christopher B Wilson
Journal:  Immunity       Date:  2009-10-08       Impact factor: 31.745

2.  Regulation of the hyaluronan synthase 2 gene by convergence in cyclic AMP response element-binding protein and retinoid acid receptor signaling.

Authors:  Katri M Makkonen; Sanna Pasonen-Seppänen; Kari Törrönen; Markku I Tammi; Carsten Carlberg
Journal:  J Biol Chem       Date:  2009-05-05       Impact factor: 5.157

  2 in total

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