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Literature DB >> 18243090

Mitochondria--a nexus for aging, calorie restriction, and sirtuins?

Abstract

Recent studies of calorie restriction in several organisms demonstrate an increase in mitochondrial activity that is associated with the salutary effects of this dietary restriction regimen. In this Essay, I speculate on how an increase in mitochondrial activity might provide benefit and discuss how diet, mitochondria, and sirtuins might interact in a pathway to slow aging and associated diseases.

Mesh：

Substances：
Sirtuins

Year: 2008 PMID： 18243090 PMCID： PMC2680180 DOI： 10.1016/j.cell.2008.01.007

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

42 in total

1. Rates of behavior and aging specified by mitochondrial function during development.

Authors: Andrew Dillin; Ao-Lin Hsu; Nuno Arantes-Oliveira; Joshua Lehrer-Graiwer; Honor Hsin; Andrew G Fraser; Ravi S Kamath; Julie Ahringer; Cynthia Kenyon
Journal: Science Date: 2002-12-05 Impact factor: 47.728

2. Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain.

Authors: M R Owen; E Doran; A P Halestrap
Journal: Biochem J Date: 2000-06-15 Impact factor: 3.857

3. Premature ageing in mice expressing defective mitochondrial DNA polymerase.

Authors: Aleksandra Trifunovic; Anna Wredenberg; Maria Falkenberg; Johannes N Spelbrink; Anja T Rovio; Carl E Bruder; Mohammad Bohlooly-Y; Sebastian Gidlöf; Anders Oldfors; Rolf Wibom; Jan Törnell; Howard T Jacobs; Nils-Göran Larsson
Journal: Nature Date: 2004-05-27 Impact factor: 49.962

4. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase.

Authors: S Imai; C M Armstrong; M Kaeberlein; L Guarente
Journal: Nature Date: 2000-02-17 Impact factor: 49.962

5. Role of AMP-activated protein kinase in mechanism of metformin action.

Authors: G Zhou; R Myers; Y Li; Y Chen; X Shen; J Fenyk-Melody; M Wu; J Ventre; T Doebber; N Fujii; N Musi; M F Hirshman; L J Goodyear; D E Moller
Journal: J Clin Invest Date: 2001-10 Impact factor: 14.808

6. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration.

Authors: Su-Ju Lin; Matt Kaeberlein; Alex A Andalis; Lori A Sturtz; Pierre-Antoine Defossez; Valeria C Culotta; Gerald R Fink; Leonard Guarente
Journal: Nature Date: 2002-07-18 Impact factor: 49.962

7. Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae.

Authors: Rozalyn M Anderson; Kevin J Bitterman; Jason G Wood; Oliver Medvedik; David A Sinclair
Journal: Nature Date: 2003-05-08 Impact factor: 49.962

8. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy.

Authors: In Hye Lee; Liu Cao; Raul Mostoslavsky; David B Lombard; Jie Liu; Nicholas E Bruns; Maria Tsokos; Frederick W Alt; Toren Finkel
Journal: Proc Natl Acad Sci U S A Date: 2008-02-22 Impact factor: 11.205

9. Calorie restriction extends yeast life span by lowering the level of NADH.

Authors: Su-Ju Lin; Ethan Ford; Marcia Haigis; Greg Liszt; Leonard Guarente
Journal: Genes Dev Date: 2004-01-01 Impact factor: 11.361

10. Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state.

Authors: Yulia Kushnareva; Anne N Murphy; Alexander Andreyev
Journal: Biochem J Date: 2002-12-01 Impact factor: 3.857

217 in total

Review 1. Regulation of SIRT1 in cellular functions: role of polyphenols.

Authors: Sangwoon Chung; Hongwei Yao; Samuel Caito; Jae-Woong Hwang; Gnanapragasam Arunachalam; Irfan Rahman
Journal: Arch Biochem Biophys Date: 2010-05-05 Impact factor: 4.013

2. Calorie restriction in mice overexpressing UCP3: evidence that prior mitochondrial uncoupling alters response.

Authors: Carmen Estey; Erin L Seifert; Céline Aguer; Cynthia Moffat; Mary-Ellen Harper
Journal: Exp Gerontol Date: 2012-03-03 Impact factor: 4.032

Review 3. Novel mitochondrial targets for neuroprotection.

Authors: Miguel A Perez-Pinzon; R Anne Stetler; Gary Fiskum
Journal: J Cereb Blood Flow Metab Date: 2012-03-28 Impact factor: 6.200

Review 4. Physiological insights gained from gene expression analysis in obesity and diabetes.

Authors: Mark P Keller; Alan D Attie
Journal: Annu Rev Nutr Date: 2010-08-21 Impact factor: 11.848

5. Does calorie restriction induce mitochondrial biogenesis? A reevaluation.

Authors: Chad R Hancock; Dong-Ho Han; Kazuhiko Higashida; Sang Hyun Kim; John O Holloszy
Journal: FASEB J Date: 2010-11-03 Impact factor: 5.191

Review 6. Effects of caloric restriction on age-related hearing loss in rodents and rhesus monkeys.

Authors: Shinichi Someya; Masaru Tanokura; Richard Weindruch; Tomas A Prolla; Tatsuya Yamasoba
Journal: Curr Aging Sci Date: 2010-02

7. Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction.

Authors: Lydia W S Finley; Jaewon Lee; Amanda Souza; Valérie Desquiret-Dumas; Kevin Bullock; Glenn C Rowe; Vincent Procaccio; Clary B Clish; Zoltan Arany; Marcia C Haigis
Journal: Proc Natl Acad Sci U S A Date: 2012-02-03 Impact factor: 11.205

8. Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response.

Authors: Weiwei Dang; George L Sutphin; Jean A Dorsey; Gabriel L Otte; Kajia Cao; Rocco M Perry; Jennifer J Wanat; Dimitra Saviolaki; Christopher J Murakami; Scott Tsuchiyama; Brett Robison; Brian D Gregory; Michiel Vermeulen; Ramin Shiekhattar; F Brad Johnson; Brian K Kennedy; Matt Kaeberlein; Shelley L Berger
Journal: Cell Metab Date: 2014-05-08 Impact factor: 27.287

9. Sirtuin 3 deficiency does not augment hypoxia-induced pulmonary hypertension.

Authors: Gregory B Waypa; Scott W Osborne; Jeremy D Marks; Sara K Berkelhamer; Jyothisri Kondapalli; Paul T Schumacker
Journal: Am J Respir Cell Mol Biol Date: 2013-12 Impact factor: 6.914

Review 10. Metabolic regulation of Sirtuins upon fasting and the implication for cancer.

Authors: Yueming Zhu; Yufan Yan; David R Gius; Athanassios Vassilopoulos
Journal: Curr Opin Oncol Date: 2013-11 Impact factor: 3.645