| Literature DB >> 18242987 |
Liming Shao1, Michael Hewitt, Thomas P Jerussi, Frank Wu, Scott Malcolm, Paul Grover, Kevin Fang, Patrick Koch, Chris Senanayake, Nandkumar Bhongle, Seth Ribe, Roger Bakale, Mark Currie.
Abstract
Tramadol is a centrally acting opioid analgesic structurally related to codeine and morphine. O-Alkyl, N-desmethyl, and non-phenol containing derivatives of tramadol were synthesized to probe their effect on metabolic stability and both in vitro and in vivo potency.Entities:
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Year: 2008 PMID： 18242987 DOI： 10.1016/j.bmcl.2008.01.051
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823