Literature DB >> 18242022

Diclofenac sodium delivery to the eye: in vitro evaluation of novel solid lipid nanoparticle formulation using human cornea construct.

Anthony A Attama1, Stephan Reichl, Christel C Müller-Goymann.   

Abstract

Solid lipid nanoparticles (SLNs) were prepared with a combination of homolipid from goat (goat fat) and phospholipid, and evaluated for diclofenac sodium (DNa) delivery to the eye using bio-engineered human cornea, produced from immortalized human corneal endothelial cells (HENC), stromal fibroblasts and epithelial cells CEPI 17 CL 4. Encapsulation efficiency was high and sustained release of DNa and high permeation through the bio-engineered cornea were achieved. Results obtained in this work showed that permeation of DNa through the cornea construct was improved by formulation as SLN modified with phospholipid.

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Year:  2007        PMID： 18242022     DOI： 10.1016/j.ijpharm.2007.12.007

Source DB:  PubMed          Journal:  Int J Pharm        ISSN： 0378-5173            Impact factor:   5.875


  25 in total

1.  Nanoparticles in the ocular drug delivery.

Authors:  Hong-Yan Zhou; Ji-Long Hao; Shuang Wang; Yu Zheng; Wen-Song Zhang
Journal:  Int J Ophthalmol       Date:  2013-06-18       Impact factor: 1.779

2.  Development and Evaluation of Diclofenac Sodium Loaded-N-Trimethyl Chitosan Nanoparticles for Ophthalmic Use.

Authors:  Rathapon Asasutjarit; Thitaree Theerachayanan; Prartana Kewsuwan; Sukitaya Veeranodha; Asira Fuongfuchat; Garnpimol C Ritthidej
Journal:  AAPS PharmSciTech       Date:  2015-01-22       Impact factor: 3.246

Review 3.  Nanoparticles for drug delivery to the anterior segment of the eye.

Authors:  Dileep R Janagam; Linfeng Wu; Tao L Lowe
Journal:  Adv Drug Deliv Rev       Date:  2017-04-06       Impact factor: 15.470

4.  Investigation of localized delivery of diclofenac sodium from poly(D,L-lactic acid-co-glycolic acid)/poly(ethylene glycol) scaffolds using an in vitro osteoblast inflammation model.

Authors:  Laura E Sidney; Thomas R J Heathman; Emily R Britchford; Arif Abed; Cheryl V Rahman; Lee D K Buttery
Journal:  Tissue Eng Part A       Date:  2014-10-07       Impact factor: 3.845

5.  Design of cationic nanostructured heterolipid matrices for ocular delivery of methazolamide.

Authors:  John Youshia; Amany O Kamel; Abdelhameed El Shamy; Samar Mansour
Journal:  Int J Nanomedicine       Date:  2012-05-17

Review 6.  Lipid Nanoparticles for Ocular Gene Delivery.

Authors:  Yuhong Wang; Ammaji Rajala; Raju V S Rajala
Journal:  J Funct Biomater       Date:  2015-06-08

7.  Design and Evaluation of Ocular Controlled Delivery System for Diclofenac Sodium.

Authors:  Zahra Jafariazar; Nasim Jamalinia; Fatemeh Ghorbani-Bidkorbeh; Seyed Alireza Mortazavi
Journal:  Iran J Pharm Res       Date:  2015       Impact factor: 1.696

8.  Solid lipid nanoparticles of guggul lipid as drug carrier for transdermal drug delivery.

Authors:  Praveen Kumar Gaur; Shikha Mishra; Suresh Purohit
Journal:  Biomed Res Int       Date:  2013-08-24       Impact factor: 3.411

9.  Design and optimization of PLGA-based diclofenac loaded nanoparticles.

Authors:  Dustin L Cooper; Sam Harirforoosh
Journal:  PLoS One       Date:  2014-01-28       Impact factor: 3.240

10.  Ocular drug delivery: a clue from nanotechnology.

Authors:  Claudio Bucolo; Filippo Drago; Salvatore Salomone
Journal:  Front Pharmacol       Date:  2012-10-25       Impact factor: 5.810
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