OBJECTIVE: Subjective quality of life (sQoL) and potentially contributing factors were investigated in individuals putatively in an early (EIPS) or late initial prodromal state (LIPS) and healthy controls (HC). METHOD: Participants comprised 58 EIPS individuals, 157 LIPS individuals and 87 HC individuals. sQoL was assessed together with locus of control (LoC), coping, demography and psychopathology. RESULTS: Putatively prodromal groups exhibited markedly lower sQoL than HC (all domains P < 0.00001). EIPS and LIPS individuals did not differ significantly. Depression was the most consistent explaining variable of sQoL in EIPS and LIPS individuals. In EIPS individuals, LoC emerged as an additional predictor. CONCLUSION: Individuals at risk for psychosis experienced a marked impairment of sQoL across all domains. This was evident even in the early state, showed no significant further deterioration during the late state and was predominantly explained by non-specific symptoms.
OBJECTIVE: Subjective quality of life (sQoL) and potentially contributing factors were investigated in individuals putatively in an early (EIPS) or late initial prodromal state (LIPS) and healthy controls (HC). METHOD:Participants comprised 58 EIPS individuals, 157 LIPS individuals and 87 HC individuals. sQoL was assessed together with locus of control (LoC), coping, demography and psychopathology. RESULTS: Putatively prodromal groups exhibited markedly lower sQoL than HC (all domains P < 0.00001). EIPS and LIPS individuals did not differ significantly. Depression was the most consistent explaining variable of sQoL in EIPS and LIPS individuals. In EIPS individuals, LoC emerged as an additional predictor. CONCLUSION: Individuals at risk for psychosis experienced a marked impairment of sQoL across all domains. This was evident even in the early state, showed no significant further deterioration during the late state and was predominantly explained by non-specific symptoms.
Authors: A Masillo; L R Valmaggia; R Saba; M Brandizzi; J F Lindau; A Solfanelli; M Curto; F Narilli; L Telesforo; G D Kotzalidis; D Di Pietro; M D'Alema; P Girardi; P Fiori Nastro Journal: Eur Child Adolesc Psychiatry Date: 2015-02-25 Impact factor: 4.785
Authors: Alison R Yung; Scott W Woods; Stephan Ruhrmann; Jean Addington; Frauke Schultze-Lutter; Barbara A Cornblatt; G Paul Amminger; Andreas Bechdolf; Max Birchwood; Stefan Borgwardt; Tyrone D Cannon; Lieuwe de Haan; Paul French; Paolo Fusar-Poli; Matcheri Keshavan; Joachim Klosterkötter; Jun Soo Kwon; Patrick D McGorry; Philip McGuire; Masafumi Mizuno; Anthony P Morrison; Anita Riecher-Rössler; Raimo K R Salokangas; Larry J Seidman; Michio Suzuki; Lucia Valmaggia; Mark van der Gaag; Stephen J Wood; Thomas H McGlashan Journal: Schizophr Bull Date: 2012-11 Impact factor: 9.306
Authors: C M Corcoran; D Kimhy; M A Parrilla-Escobar; V L Cressman; A D Stanford; J Thompson; S Ben David; A Crumbley; S Schobel; H Moore; D Malaspina Journal: Psychol Med Date: 2010-05-06 Impact factor: 7.723
Authors: Christoph U Correll; Marta Hauser; Andrea M Auther; Barbara A Cornblatt Journal: J Child Psychol Psychiatry Date: 2010-02-26 Impact factor: 8.982
Authors: Paolo Fusar-Poli; Stefan Borgwardt; Andreas Bechdolf; Jean Addington; Anita Riecher-Rössler; Frauke Schultze-Lutter; Matcheri Keshavan; Stephen Wood; Stephan Ruhrmann; Larry J Seidman; Lucia Valmaggia; Tyrone Cannon; Eva Velthorst; Lieuwe De Haan; Barbara Cornblatt; Ilaria Bonoldi; Max Birchwood; Thomas McGlashan; William Carpenter; Patrick McGorry; Joachim Klosterkötter; Philip McGuire; Alison Yung Journal: JAMA Psychiatry Date: 2013-01 Impact factor: 21.596
Authors: Doreen M Olvet; Ricardo E Carrión; Andrea M Auther; Barbara A Cornblatt Journal: Early Interv Psychiatry Date: 2013-08-22 Impact factor: 2.732