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Literature DB >> 182402

Pathogenesis of Machupo virus infection in primates.

G A Eddy, S K Scott, F S Wagner, O M Brand.

Abstract

Experimental Machupo virus infection of rhesus and cynomolgus monkeys produced a severe illness consisting of an initial clinical phase and a later neurological phase. Cumulative mortality during the two phases was 80% and 95% respectively. Attempts to alter the pathogenesis with decomplementation or immunosuppression resulted in earlier deaths of the monkeys.

Entities: Disease Species

Mesh：

Substances：

Year: 1975 PMID： 182402 PMCID： PMC2366670

Source DB: PubMed Journal: Bull World Health Organ ISSN： 0042-9686 Impact factor: 9.408

5 in total

1. VIRUS ISOLATIONS FROM HUMAN CASES OF HEMORRHAGIC FEVER IN BOLIVIA.

Authors: K M JOHNSON; N H WIEBENGA; R B MACKENZIE; M L KUNS; N M TAURASO; A SHELOKOV; P A WEBB; G JUSTINES; H K BEYE
Journal: Proc Soc Exp Biol Med Date: 1965-01

2. A plaque neutralization method for arboviruses.

Authors: E Earley; P H Peralta; K M Johnson
Journal: Proc Soc Exp Biol Med Date: 1967-07

3. Hemorrhagic fever in Cochabamba, Bolivia, 1971.

Authors: C J Peters; R W Kuehne; R R Mercado; R H Le Bow; R O Spertzel; P A Webb
Journal: Am J Epidemiol Date: 1974-06 Impact factor: 4.897

4. The measurement of specific antibodies in Bolivian hemorrhagic fever by neutralization of virus plaques.

Authors: P A Webb; K M Johnson; R B Mackenzie
Journal: Proc Soc Exp Biol Med Date: 1969-03

5. Pathogenesis of chronic disease associated with persistent lymphocytic choriomeningitis viral infection. II. Relationship of the anti-lymphocytic choriomeningitis immune response to tissue injury in chronic lymphocytic choriomeningitis disease.

Authors: M B Oldstone; F J Dixon
Journal: J Exp Med Date: 1970-01-01 Impact factor: 14.307

5 in total

12 in total

1. Directions for future research on the pathogenesis of arenaviral infections.

Authors: N Nathanson
Journal: Bull World Health Organ Date: 1975 Impact factor: 9.408

2. Protection of monkeys against Machupo virus by the passive administration of Bolivian haemorrhagic fever immunoglobulin (human origin).

Authors: G A Eddy; F S Wagner; S K Scott; B J Mahlandt
Journal: Bull World Health Organ Date: 1975 Impact factor: 9.408

Review 3. Epidemiology and pathogenesis of Bolivian hemorrhagic fever.

Authors: Michael Patterson; Ashley Grant; Slobodan Paessler
Journal: Curr Opin Virol Date: 2014-03-15 Impact factor: 7.090

Review 4. Drug discovery technologies and strategies for Machupo virus and other New World arenaviruses.

Authors: Sheli R Radoshitzky; Jens H Kuhn; Fabian de Kok-Mercado; Peter B Jahrling; Sina Bavari
Journal: Expert Opin Drug Discov Date: 2012-05-19 Impact factor: 6.098

5. Virulence alterations of tacaribe virus infection in adult mice: lethal model for encephalitis.

Authors: R R Rosato; M R Elwell; G A Eddy
Journal: Arch Virol Date: 1978 Impact factor: 2.574

Review 6. Progress in the experimental therapy of severe arenaviral infections.

Authors: Brian B Gowen; Mike Bray
Journal: Future Microbiol Date: 2011-12 Impact factor: 3.165

7. Rescue of a recombinant Machupo virus from cloned cDNAs and in vivo characterization in interferon (αβ/γ) receptor double knockout mice.

Authors: Michael Patterson; Alexey Seregin; Cheng Huang; Olga Kolokoltsova; Jennifer Smith; Milagros Miller; Jeanon Smith; Nadezhda Yun; Allison Poussard; Ashley Grant; Bersabeh Tigabu; Aida Walker; Slobodan Paessler
Journal: J Virol Date: 2013-11-27 Impact factor: 5.103