Literature DB >> 18240049

Drilling skull plus injection of urokinase in the treatment of epidural haematoma: a preliminary study.

Weiguo Liu1, Li Ma, Liang Wen, Fang Shen, Hansong Sheng, Bo Zhou, Weiwei Hu, Xiujue Zheng, Xiaofeng Yang.   

Abstract

PRIMARY
OBJECTIVE: This study was performed to evaluate the effectiveness of a minimally invasive approach to manage patients with epidural haematoma (EDH). The surgical indication and key points were investigated. RESEARCH
DESIGN: Descriptive, retrospective study. METHODS AND PROCEDURES: Twenty-one patients with traumatic EDH were treated through the following method: After anaesthesia, twist drill trepanations were performed followed by a placement of drainage tubes. Twenty ku urokinase in 3 ml saline was injected into the haematoma cyst through the tube, which was closed for 3 hours before connection to a vacuum ball with negative pressure. The injection was repeated three times a day after operation. The fibrinolytic agents were not used in the 'acute group' because of the risk of rebleeding. CT scans were performed according to the changes of clinical manifestations. MAIN OUTCOMES AND
RESULTS: The drainage tubes were left for 3-5 days before most clots were resolved. The patients discharged after 7 days' hospitalization on average. No infections or recurrence of EDHs were observed in this series.
CONCLUSION: Drilling skull plus injection of urokinase through drainage tube is a safe and effective method with less injury in the treatment of a selected part of patients with EDHs.

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Year:  2008        PMID: 18240049     DOI: 10.1080/02699050801895407

Source DB:  PubMed          Journal:  Brain Inj        ISSN: 0269-9052            Impact factor:   2.311


  6 in total

1.  The Effectiveness of Subdural Drains Using Urokinase after Burr Hole Evacuation of Subacute Subdural Hematoma in Elderly Patients: A Prelimilary Report.

Authors:  Chang-Gi Yeo; Woo-Yeol Jeon; Seong-Ho Kim; Oh-Lyong Kim; Min-Su Kim
Journal:  Korean J Neurotrauma       Date:  2016-10-31

2.  Trephination mini-craniectomy for traumatic posterior fossa epidural hematomas in selected pediatric patients.

Authors:  Han-Song Sheng; Chao-Guo You; Liang Yang; Nu Zhang; Jian Lin; Fen-Chun Lin; Mao-De Wang
Journal:  Chin J Traumatol       Date:  2017-06-22

3.  Burr Hole Drainage with Urokinase Irrigation for the Treatment of Acute Subdural Hematoma: A Case Report.

Authors:  Seong-Woo Cho; Seung-Won Choi; Jeongwook Lim; Hyon-Jo Kwon; Seon-Hwan Kim; Hyeon-Song Koh; Jin-Young Youm; Shi-Hun Song
Journal:  Korean J Neurotrauma       Date:  2018-10-31

4.  Delayed Operation of Acute Subdural Hematoma in Subacute Stage by Trephine Drainage using Urokinase.

Authors:  Hyeon Gu Kang; Kyu Yong Cho; Rae Seop Lee; Jun Seob Lim
Journal:  Korean J Neurotrauma       Date:  2019-10-18

5.  Minimally Invasive Surgical Treatment of Acute Epidural Hematoma: Case Series.

Authors:  Weijun Wang
Journal:  Biomed Res Int       Date:  2016-04-06       Impact factor: 3.411

6.  Emergency bedside evacuation of a subset of large postoperative epidural hematomas after neurosurgical procedures.

Authors:  Hecheng Ren; Long Yin; Lin Ma; Ming Wei; Xiaodong Ma
Journal:  Medicine (Baltimore)       Date:  2018-07       Impact factor: 1.889

  6 in total

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