PURPOSE: We evaluated the effectiveness of multidetector-row computed tomography (MD-CT) for detecting axillary lymph nodal status (ALNS) in patients with breast cancer. METHODS: We reviewed 42 patients with breast cancer. A metastatic lymph node on MD-CT was defined as oval or round, with more than 5 mm on the short axis. We evaluated ALNS preoperatively by both palpation and MD-CT findings and performed sentinel lymph node biopsy (SLNB) and complete axillary lymph node dissection (ALND). RESULTS: For establishing the ALNS, MD-CT showed a sensitivity of 76.9%, a specificity of 96.6%, and an accuracy of 90.5%. On the basis of the MD-CT findings, misdiagnosis was made in 4 of the 42 patients, only one of which was false positive. On the other hand, one patient with a histologically negative sentinel lymph node (SLN) result had metastasis only in a non-SLN. Preoperative MD-CT showed a positive node in this patient. CONCLUSIONS: Multidetector-row computed tomography assists in identifying women who require ALND without SLNB, with sufficient positive predictive value. False-negative detection by SLNB could be avoided with careful interpretation of the axillary lymph nodes shown by MD-CT.
PURPOSE: We evaluated the effectiveness of multidetector-row computed tomography (MD-CT) for detecting axillary lymph nodal status (ALNS) in patients with breast cancer. METHODS: We reviewed 42 patients with breast cancer. A metastatic lymph node on MD-CT was defined as oval or round, with more than 5 mm on the short axis. We evaluated ALNS preoperatively by both palpation and MD-CT findings and performed sentinel lymph node biopsy (SLNB) and complete axillary lymph node dissection (ALND). RESULTS: For establishing the ALNS, MD-CT showed a sensitivity of 76.9%, a specificity of 96.6%, and an accuracy of 90.5%. On the basis of the MD-CT findings, misdiagnosis was made in 4 of the 42 patients, only one of which was false positive. On the other hand, one patient with a histologically negative sentinel lymph node (SLN) result had metastasis only in a non-SLN. Preoperative MD-CT showed a positive node in this patient. CONCLUSIONS: Multidetector-row computed tomography assists in identifying women who require ALND without SLNB, with sufficient positive predictive value. False-negative detection by SLNB could be avoided with careful interpretation of the axillary lymph nodes shown by MD-CT.
Authors: J Feu; F Tresserra; R Fábregas; B Navarro; P J Grases; J C Suris; A Fernández-Cíd; X Alegret Journal: Radiology Date: 1997-12 Impact factor: 11.105
Authors: N Tohnosu; K Okuyama; Y Koide; T Kikuchi; T Awano; H Matsubara; T Sano; H Nakaichi; Y Funami; K Matsushita Journal: Surg Today Date: 1993 Impact factor: 2.549
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Authors: Janna Morawitz; Nils-Martin Bruckmann; Frederic Dietzel; Tim Ullrich; Ann-Kathrin Bittner; Oliver Hoffmann; Eugen Ruckhäberle; Svjetlana Mohrmann; Lena Häberle; Marc Ingenwerth; Daniel Benjamin Abrar; Lino Morris Sawicki; Katharina Breuckmann; Wolfgang Peter Fendler; Ken Herrmann; Christian Buchbender; Gerald Antoch; Lale Umutlu; Julian Kirchner Journal: Eur J Nucl Med Mol Imaging Date: 2021-09-03 Impact factor: 9.236