Literature DB >> 18239459

A context dependent role for Wnt signaling in tumorigenesis and stem cells.

Igor Matushansky1, Robert G Maki, Carlos Cordon-Cardo.   

Abstract

The Wnt signal transduction pathway coordinates myriad activities, from development and differentiation to proliferation and tumorigenesis. What is perhaps most remarkable is that Wnt signaling is able to accomplish this diverse set of activities in a cell-specific and differentiation stage-dependent manner. In this review, we will highlight the diverse effect of Wnt signaling on three types of tissue stem cells and their corresponding malignancies.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18239459     DOI： 10.4161/cc.7.6.5569

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


  11 in total

1.  A transgenic, mesodermal specific, Dkk1 mouse model recapitulates a spectrum of human congenital limb reduction defects.

Authors:  Filemon Dela Cruz; Melissa Terry; Igor Matushansky
Journal:  Differentiation       Date:  2012-03-08       Impact factor: 3.880

2.  Dynamic expression of a LEF-EGFP Wnt reporter in mouse development and cancer.

Authors:  Nicolas Currier; Kathleen Chea; Mirka Hlavacova; Daniel J Sussman; David C Seldin; Isabel Dominguez
Journal:  Genesis       Date:  2010-03       Impact factor: 2.487

Review 3.  Perspectives on cancer stem cells in osteosarcoma.

Authors:  Upal Basu-Roy; Claudio Basilico; Alka Mansukhani
Journal:  Cancer Lett       Date:  2012-05-29       Impact factor: 8.679

4.  ARTEMIS stabilizes the genome and modulates proliferative responses in multipotent mesenchymal cells.

Authors:  Sarah A Maas; Nina M Donghia; Kathleen Tompkins; Oded Foreman; Kevin D Mills
Journal:  BMC Biol       Date:  2010-10-27       Impact factor: 7.431

Review 5.  MFH classification: differentiating undifferentiated pleomorphic sarcoma in the 21st Century.

Authors:  Igor Matushansky; Elizabeth Charytonowicz; Joslyn Mills; Sara Siddiqi; Todd Hricik; Carlos Cordon-Cardo
Journal:  Expert Rev Anticancer Ther       Date:  2009-08       Impact factor: 4.512

6.  The pleiotropic phenotype of Apc mutations in the mouse: allele specificity and effects of the genetic background.

Authors:  Richard B Halberg; Xiaodi Chen; James M Amos-Landgraf; Alanna White; Kristin Rasmussen; Linda Clipson; Cheri Pasch; Ruth Sullivan; Henry C Pitot; William F Dove
Journal:  Genetics       Date:  2008-08-24       Impact factor: 4.562

Review 7.  Epigenetic remodeling of chromatin architecture: exploring tumor differentiation therapies in mesenchymal stem cells and sarcomas.

Authors:  Sara Siddiqi; Joslyn Mills; Igor Matushansky
Journal:  Curr Stem Cell Res Ther       Date:  2010-03       Impact factor: 3.828

8.  Mammary stem cells and cancer: roles of Wnt signaling in plain view.

Authors:  Alexander M Many; Anthony M C Brown
Journal:  Breast Cancer Res       Date:  2010-09-22       Impact factor: 6.466

9.  Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling.

Authors:  Junfang Zhang; Hailong Cao; Bing Zhang; Hanwei Cao; Xiuqin Xu; Hang Ruan; Tingting Yi; Li Tan; Rui Qu; Gang Song; Bangmao Wang; Tianhui Hu
Journal:  J Cell Mol Med       Date:  2013-09-09       Impact factor: 5.310

10.  Expression analysis of E-cadherin, Slug and GSK3beta in invasive ductal carcinoma of breast.

Authors:  Chandra P Prasad; Gayatri Rath; Sandeep Mathur; Dinesh Bhatnagar; Rajinder Parshad; Ranju Ralhan
Journal:  BMC Cancer       Date:  2009-09-14       Impact factor: 4.430
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.