| Literature DB >> 182382 |
Abstract
We have selected Chinese hamster ovary (CHO) cells resistant to infection by encephalomycarditis (EMC) virus. Thus far, we have obtained five lines resistant to EMC, all of which manifest different phenotypes. Three of the five are not persistently infected with virus, while two lines produce infectious virus and grow in its presence. The nonpersistently infected lines exhibit different resistance profiles to the other viruses we have tested, and they are stable in nonselective growth conditions. Their resistance appears to be due to a genetic alteration in the cell.Entities:
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Year: 1976 PMID： 182382 DOI： 10.1016/0092-8674(76)90221-x
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582