| Literature DB >> 18232703 |
Jinhua J Song1, Zhulin Tan, Jonathan T Reeves, Daniel R Fandrick, Nathan K Yee, Chris H Senanayake.
Abstract
N-Heterocyclic carbenes (NHCs) were found to catalyze the silyl transfer from trialkylsilyl ketene acetals to ketones. In the presence of a catalytic amount of NHC 3 (IAd, 0.1 to 5 mol %), a series of enolizable ketones as well as cyclohexanecarboxaldehyde were efficiently converted into the corresponding silyl enol ethers at 23 degrees C in THF.Entities:
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Year: 2008 PMID： 18232703 DOI： 10.1021/ol703025b
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005