Literature DB >> 18231957

1,25-dihydroxyvitamin D-mediated hypercalcemia in ovarian dysgerminoma.

Masahito Hibi1, Hibi Masahito, Fujio Hara, Hirokazu Tomishige, Yoshihisa Nishida, Takazumi Kato, Naotake Okumura, Takashi Hashimoto, Ryoichi Kato.   

Abstract

Humoral hypercalcemia of malignancy (HHM) is a rare complication of malignant pediatric tumors, specifically those that secrete humoral factor(s), such as parathyroid hormone-related peptide (PTHrP). The authors report a case of severe hypercalcemia associated with ovarian dysgerminoma in a 10-year-old girl. In this case, the humoral factor was considered to be 1,25-dihydroxyvitamin D. HHM is extremely resistant to medical therapy. Therefore, tumor resection or volume reduction is necessary to control serum calcium levels.

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Year:  2008        PMID： 18231957     DOI： 10.1080/08880010701774033

Source DB:  PubMed          Journal:  Pediatr Hematol Oncol        ISSN： 0888-0018            Impact factor:   1.969


  8 in total

1.  Twist on a classic: vitamin D and hypercalcaemia of malignancy.

Authors:  Juan C Osorio; Masha G Jones; Nina Schatz-Siemers; Stephanie J Tang
Journal:  BMJ Case Rep       Date:  2017-11-23

Review 2.  Hypercalcemia of malignancy and new treatment options.

Authors:  Hillel Sternlicht; Ilya G Glezerman
Journal:  Ther Clin Risk Manag       Date:  2015-12-04       Impact factor: 2.423

Review 3.  Treatment of malignancy-associated hypercalcemia with cinacalcet: a paradigm shift.

Authors:  Sondra O'Callaghan; Hanford Yau
Journal:  Endocr Connect       Date:  2021-01       Impact factor: 3.335

4.  Hypercalcemia associated with a malignant brenner tumor arising from a mature cystic teratoma.

Authors:  Michael C Honigberg; Leslie S Bradford; Anand M Prabhakar; Lida P Hariri; Annekathryn Goodman
Journal:  Case Rep Oncol       Date:  2012-11-06

5.  Unusual behaviour of an unusual tumour: calcitriol-induced hypercalcaemia in metastatic oesophageal neuroendocrine carcinoma.

Authors:  Filip Ionescu; Ioana Petrescu; Maria Marin
Journal:  BMJ Case Rep       Date:  2020-08-25

Review 6.  Hypercalcemia in metastatic GIST caused by systemic elevated calcitriol: a case report and review of the literature.

Authors:  Katrine Hygum; Christian Nielsen Wulff; Torben Harsløf; Anders Kindberg Boysen; Philip Blach Rossen; Bente Lomholt Langdahl; Akmal Ahmed Safwat
Journal:  BMC Cancer       Date:  2015-10-24       Impact factor: 4.430

7.  Physiologic and pathophysiologic roles of extra renal CYP27b1: Case report and review.

Authors:  Daniel D Bikle; Sophie Patzek; Yongmei Wang
Journal:  Bone Rep       Date:  2018-02-26

8.  Hypercalcemia Due to Paraneoplastic Production of 1,25- Dihydroxyvitamin D in a Young Female with Dysgerminoma.

Authors:  Iqra Iqbal; Muhammad Atique Alam Khan; Yasir Khan; Nishanth Thalambedu; Samavia Munir
Journal:  Cureus       Date:  2019-11-08
  8 in total

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