OBJECTIVES: Investigating relationships between potential occupational risk factors and lymphoid malignancy (LM). METHODS: We conducted a multicenter hospital-based case-control study in France between 2000 and 2004, including 824 incident cases of non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL), multiple myeloma, and "lymphoproliferative syndrome" and 752 frequency-matched controls. Data were collected through face-to-face standardized and detailed interviews. RESULTS: Farming was significantly associated with NHL (odds ratio [OR] = 1.4 [1.0 to 2.0]) and, although not significantly, with lymphoproliferative syndrome and multiple myeloma. ORs were higher for longest durations of exposure. Self-declared exposure to pesticides was significantly associated with NHL (OR = 1.8 [1.2 to 2.7]) and HL (OR = 2.2 [1.0 to 4.7]). Neither solvent-related jobs nor self-reported exposure to solvents were related to LM. Systematic screening based on job titles did not evidence any other association. CONCLUSIONS: The results support the hypothesis that farming plays a role in most types of LM.
OBJECTIVES: Investigating relationships between potential occupational risk factors and lymphoid malignancy (LM). METHODS: We conducted a multicenter hospital-based case-control study in France between 2000 and 2004, including 824 incident cases of non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL), multiple myeloma, and "lymphoproliferative syndrome" and 752 frequency-matched controls. Data were collected through face-to-face standardized and detailed interviews. RESULTS: Farming was significantly associated with NHL (odds ratio [OR] = 1.4 [1.0 to 2.0]) and, although not significantly, with lymphoproliferative syndrome and multiple myeloma. ORs were higher for longest durations of exposure. Self-declared exposure to pesticides was significantly associated with NHL (OR = 1.8 [1.2 to 2.7]) and HL (OR = 2.2 [1.0 to 4.7]). Neither solvent-related jobs nor self-reported exposure to solvents were related to LM. Systematic screening based on job titles did not evidence any other association. CONCLUSIONS: The results support the hypothesis that farming plays a role in most types of LM.
Authors: L Grandin; L Orsi; X Troussard; A Monnereau; C Berthou; P Fenaux; G Marit; P Soubeyran; F Huguet; N Milpied; M Leporrier; D Hemon; J Clavel Journal: Cancer Causes Control Date: 2007-11-27 Impact factor: 2.506
Authors: Alain Monnereau; Susan L Slager; Ann Maree Hughes; Alex Smith; Bengt Glimelius; Thomas M Habermann; Sonja I Berndt; Anthony Staines; Aaron D Norman; James R Cerhan; Joshua N Sampson; Lindsay M Morton; Jacqueline Clavel Journal: J Natl Cancer Inst Monogr Date: 2014-08
Authors: Helen H McDuffie; Punam Pahwa; Chandima P Karunanayake; John J Spinelli; James A Dosman Journal: BMC Cancer Date: 2009-02-27 Impact factor: 4.430