| Literature DB >> 18230962 |
Daniele Focosi1, Richard Eric Kast, Edoardo Benedetti, Federico Papineschi, Sara Galimberti, Mario Petrini.
Abstract
We report on a 22-year-old female who developed aplastic anemia after administration of phenobarbital for 6 years. Being refractory to steroid and anti-lymphocyte serum, the patient received allogeneic stem cell transplantation, achieving complete remission. We discuss here the potential mechanisms by which phenobarbital and other anti-epileptic drugs can cause aplastic anemia and review the literature for previous case reports and epidemiological studies. 2008 S. Karger AG, BaselEntities:
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Year: 2008 PMID： 18230962 DOI： 10.1159/000114096
Source DB: PubMed Journal: Acta Haematol ISSN： 0001-5792 Impact factor: 2.195