Literature DB >> 18229778

Sinonasal malignancies: a 10-year review in a tertiary health institution.

Ayotunde J Fasunla1, Akeem O Lasisi.   

Abstract

Sinonasal malignancy is a cause of otorhinolaryngologic morbidity and mortality in West Africa. However, there is a dearth of information in the literature on its clinicopathologic presentation in West Africa. It is our aim to determine the prevalence of sinonasal malignancy and highlight the clinicopathologic features in our environment. A 10-year retrospective review of cases with histologically diagnosed malignant sinonasal tumors in University College Hospital, Ibadan, Oyo State, Nigeria was carried out. There were 82 cases-56 (68.29%) males and 26 (31.71%) females-whose ages ranged from 4-69 years. Epistaxis, rhinorrhea and nasal blockage were seen in all patients; other symptoms were facial [76 (93%)], oral cavity [48 (59%)], ophthalmic [33 (40%)] and [otologic 21 (25%)]. Squamous cell carcinoma accounted for 69/75 (92%) of epithelial tumors, and malignant lymphoma accounted for 4/7 (57%) of nonepithelial tumors. Advanced disease was the predominant presentation in our series, stage 3 in 59 (79%) and stage 4 in 12 (16%) cases. Therefore, health education on early presentation to hospitals and efforts at early detection of the disease are needed in order to achieve cure. Industrial workers should always wear face masks to protect their nasal cavity.

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Year:  2007        PMID: 18229778      PMCID: PMC2575924     

Source DB:  PubMed          Journal:  J Natl Med Assoc        ISSN: 0027-9684            Impact factor:   1.798


  16 in total

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Journal:  J Laryngol Otol       Date:  2000-07       Impact factor: 1.469

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Journal:  Otolaryngol Clin North Am       Date:  1995-12       Impact factor: 3.346

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Journal:  Int J Cancer       Date:  1973-07-15       Impact factor: 7.396

4.  Cancer of the nasal cavity and paranasal sinuses.

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Journal:  J Laryngol Otol       Date:  1972-03       Impact factor: 1.469

5.  Sinonasal verrucous carcinoma with oral invasion.

Authors:  P Karthikeya; V G Mahima; G Bhavna
Journal:  Indian J Dent Res       Date:  2006 Apr-Jun

Review 6.  Pathogenetic and histogenetic features of HIV-associated Hodgkin's disease.

Authors:  R Dolcetti; M Boiocchi; A Gloghini; A Carbone
Journal:  Eur J Cancer       Date:  2001-07       Impact factor: 9.162

7.  Sinonasal cancer and occupational exposures: a pooled analysis of 12 case-control studies.

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Journal:  Cancer Causes Control       Date:  2002-03       Impact factor: 2.506

Review 8.  Nasal obstruction due to benign and malignant neoplasms.

Authors:  A Komisar
Journal:  Otolaryngol Clin North Am       Date:  1989-04       Impact factor: 3.346

9.  Sinonasal adenocarcinoma: evidence for histogenetic divergence of the enteric and nonenteric phenotypes.

Authors:  Hong-Ran Choi; Erich M Sturgis; Asif Rashid; Franco DeMonte; Mario A Luna; John G Batsakis; Adel K El-Naggar
Journal:  Hum Pathol       Date:  2003-11       Impact factor: 3.466

10.  Malignant neoplasms of the maxillary antrum in Nigerians.

Authors:  G T Arotiba
Journal:  West Afr J Med       Date:  1998 Jul-Sep
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  13 in total

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2.  Clinico-pathological profile of sinonasal masses: an experience in national ear care center Kaduna, Nigeria.

Authors:  Aminu Bakari; Olushola A Afolabi; Adeyi A Adoga; Aliyu M Kodiya; Babagana M Ahmad
Journal:  BMC Res Notes       Date:  2010-07-09

3.  Cataract surgical outcomes in diabetic patients: case control study.

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4.  Factors contributing to poor management outcome of sinonasal malignancies in South-west Nigeria.

Authors:  A J Fasunla; S A Ogunkeyede
Journal:  Ghana Med J       Date:  2013-03

Review 5.  Malignant neoplasms of the sinonasal tract: report of 71 patients and literature review and analysis.

Authors:  Bijan Khademi; Azadeh Moradi; Sara Hoseini; Mohammad Mohammadianpanah
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6.  Clinico-pathological profile of sinonasal masses: a study from a tertiary care hospital of India.

Authors:  A Lathi; M M A Syed; P Kalakoti; D Qutub; S P Kishve
Journal:  Acta Otorhinolaryngol Ital       Date:  2011-12       Impact factor: 2.124

7.  Epidemiological Survey of Sinonasal Malignancy in North-East Iran.

Authors:  Mehdi Poursadegh; Farid Poursadegh; Majid Esmaeili; Mehdi Bakhshaee
Journal:  Iran J Otorhinolaryngol       Date:  2015-05

8.  Paranasal sinuses malignancies: A 12-year review of clinical characteristics.

Authors:  S-A Danesh-Sani; A Sarafraz; M Chamani; H Derakhshandeh
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2016-09-01

9.  An audit of ear, nose and throat diseases in a tertiary health institution in South-western Nigeria.

Authors:  Ayotunde James Fasunla; Musa Samdi; Onyekwere George Nwaorgu
Journal:  Pan Afr Med J       Date:  2013-01-01

10.  The small round blue cell tumors of the sinonasal area: histological and immunohistochemical findings.

Authors:  Mohammad J Ashraf; Leila Beigomi; Negar Azarpira; Bita Geramizadeh; Bijan Khademi; Afsoon Hakimzadeh; Elham Abedi
Journal:  Iran Red Crescent Med J       Date:  2013-06-05       Impact factor: 0.611

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