Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Myodys, a full-length dystrophin plasmid vector for Duchenne and Becker muscular dystrophy gene therapy.

Literature DB >> 18228186

Myodys, a full-length dystrophin plasmid vector for Duchenne and Becker muscular dystrophy gene therapy.

Abstract

Transgene SA is developing Myodys, a non-viral plasmid gene therapy for the potential treatment of Duchenne muscular dystrophy and Becker muscular dystrophy. Phase I clinical trials have been completed, and a phase II clinical trial is planned.

Entities: Disease Gene

Mesh：

Substances：
Dystrophin

Year: 2008 PMID： 18228186

Source DB: PubMed Journal: Curr Opin Mol Ther ISSN： 1464-8431

Keyword Cloud
Cited

8 in total

1. Systemic gene transfer to skeletal muscle using reengineered AAV vectors.

Authors: Jana L Phillips; Julia Hegge; Jon A Wolff; R Jude Samulski; Aravind Asokan
Journal: Methods Mol Biol Date: 2011

2. Duchenne muscular dystrophy gene therapy: Lost in translation?

Authors: Dongsheng Duan
Journal: Res Rep Biol Date: 2011-03

3. Dose response in rodents and nonhuman primates after hydrodynamic limb vein delivery of naked plasmid DNA.

Authors: Christine I Wooddell; Julia O Hegge; Guofeng Zhang; Magdolna G Sebestyén; Mark Noble; Jacob B Griffin; Loretta V Pfannes; Hans Herweijer; James E Hagstrom; Serge Braun; Thierry Huss; Jon A Wolff
Journal: Hum Gene Ther Date: 2011-04-18 Impact factor: 5.695

Myodys, a full-length dystrophin plasmid vector for Duchenne and Becker muscular dystrophy gene therapy.

1. Systemic gene transfer to skeletal muscle using reengineered AAV vectors.

2. Duchenne muscular dystrophy gene therapy: Lost in translation?

3. Dose response in rodents and nonhuman primates after hydrodynamic limb vein delivery of naked plasmid DNA.

Review 4. Duchenne muscular dystrophy gene therapy in the canine model.

Review 5. Nanotherapy for Duchenne muscular dystrophy.

6. Dystrophin Gene Replacement and Gene Repair Therapy for Duchenne Muscular Dystrophy in 2016: An Interview.

Review 7. Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy.

Review 8. Systemic AAV Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy.