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Literature DB >> 18227300

A tribute to Dr. Paul A. J. Janssen: entrepreneur extraordinaire, innovative scientist, and significant contributor to anesthesiology.

Theodore H Stanley¹, Talmage D Egan, Hugo Van Aken.

Abstract

Dr. Paul Janssen was the founder of Janssen Pharmaceutica and the developer of over 80 pharmaceutical compounds that proved useful in human, botanical, and veterinary medicine. He and his coworkers synthesized the fentanyl family of drugs, many other potent analgesics, droperidol, etomidate, and numerous other important medicines that were extremely useful in psychiatry, parasitology, gastroenterology, cardiology, virology, and immunology. Anesthesiology and medicine as a whole have benefited a great deal from his resourcefulness, creativity, and entrepreneurial spirit.

Entities: Chemical Species

Mesh：

Substances：
Fentanyl

Year: 2008 PMID： 18227300 DOI： 10.1213/ane.0b013e3181605add

Source DB: PubMed Journal: Anesth Analg ISSN： 0003-2999 Impact factor: 5.108

Keyword Cloud
Cited

14 in total

Review 1. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications.

Authors: Ruben S Vardanyan; Victor J Hruby
Journal: Future Med Chem Date: 2014-03 Impact factor: 3.808

2. Nasal delivery of fentanyl.

Authors: Peter Watts; Alan Smith; Michael Perelman
Journal: Drug Deliv Transl Res Date: 2013-02 Impact factor: 4.617

Review 3. Fentanyl Formulations in the Management of Pain: An Update.

Authors: Stephan A Schug; Sonya Ting
Journal: Drugs Date: 2017-05 Impact factor: 9.546

Review 4. Fentanyl: Receptor pharmacology, abuse potential, and implications for treatment.

Authors: Sandra D Comer; Catherine M Cahill
Journal: Neurosci Biobehav Rev Date: 2018-12-05 Impact factor: 8.989

5. Design, synthesis, and biological evaluation of C₆-difluoromethylenated epoxymorphinan Mu opioid receptor antagonists.

Authors: Andrew J Kassick; Anny Treat; Nestor Tomycz; Michael G Feasel; Benedict J Kolber; Saadyah Averick
Journal: RSC Med Chem Date: 2021-11-02

6. Novel Dual-Target μ-Opioid Receptor and Dopamine D₃ Receptor Ligands as Potential Nonaddictive Pharmacotherapeutics for Pain Management.

Authors: Alessandro Bonifazi; Francisco O Battiti; Julie Sanchez; Saheem A Zaidi; Eric Bow; Mariia Makarova; Jianjing Cao; Anver Basha Shaik; Agnieszka Sulima; Kenner C Rice; Vsevolod Katritch; Meritxell Canals; J Robert Lane; Amy Hauck Newman
Journal: J Med Chem Date: 2021-05-20 Impact factor: 8.039

10. Improvement of Pain Relief of Fentanyl Citrate Drug Encapsulated in Nanostructured Lipid Carrier: Drug Formulation, Parameter Optimization, in vitro and in vivo Studies.

Authors: Mohammad Amin Bahrami; Nafiseh Farhadian; Mohammad Karimi; Arash Forouzan; Kambiz Masoumi
Journal: Drug Des Devel Ther Date: 2020-05-25 Impact factor: 4.162

A tribute to Dr. Paul A. J. Janssen: entrepreneur extraordinaire, innovative scientist, and significant contributor to anesthesiology.

Review 1. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications.

2. Nasal delivery of fentanyl.

Review 3. Fentanyl Formulations in the Management of Pain: An Update.

Review 4. Fentanyl: Receptor pharmacology, abuse potential, and implications for treatment.

5. Design, synthesis, and biological evaluation of C₆-difluoromethylenated epoxymorphinan Mu opioid receptor antagonists.

6. Novel Dual-Target μ-Opioid Receptor and Dopamine D₃ Receptor Ligands as Potential Nonaddictive Pharmacotherapeutics for Pain Management.

Review 7. New drugs and devices from 2011 - 2012 that might change your practice.

Review 8. Misuse of Novel Synthetic Opioids: A Deadly New Trend.

Review 9. Fentanyls continue to replace heroin in the drug arena: the cases of ocfentanil and carfentanil.

10. Improvement of Pain Relief of Fentanyl Citrate Drug Encapsulated in Nanostructured Lipid Carrier: Drug Formulation, Parameter Optimization, in vitro and in vivo Studies.

A tribute to Dr. Paul A. J. Janssen: entrepreneur extraordinaire, innovative scientist, and significant contributor to anesthesiology.

Review 1. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications.

2. Nasal delivery of fentanyl.

Review 3. Fentanyl Formulations in the Management of Pain: An Update.

Review 4. Fentanyl: Receptor pharmacology, abuse potential, and implications for treatment.

5. Design, synthesis, and biological evaluation of C6-difluoromethylenated epoxymorphinan Mu opioid receptor antagonists.

6. Novel Dual-Target μ-Opioid Receptor and Dopamine D3 Receptor Ligands as Potential Nonaddictive Pharmacotherapeutics for Pain Management.

Review 7. New drugs and devices from 2011 - 2012 that might change your practice.

Review 8. Misuse of Novel Synthetic Opioids: A Deadly New Trend.

Review 9. Fentanyls continue to replace heroin in the drug arena: the cases of ocfentanil and carfentanil.

10. Improvement of Pain Relief of Fentanyl Citrate Drug Encapsulated in Nano﻿structured Lipid Carrier: Drug Formulation, Parameter Optimization, in vitro and in vivo Studies.

5. Design, synthesis, and biological evaluation of C₆-difluoromethylenated epoxymorphinan Mu opioid receptor antagonists.

6. Novel Dual-Target μ-Opioid Receptor and Dopamine D₃ Receptor Ligands as Potential Nonaddictive Pharmacotherapeutics for Pain Management.

10. Improvement of Pain Relief of Fentanyl Citrate Drug Encapsulated in Nanostructured Lipid Carrier: Drug Formulation, Parameter Optimization, in vitro and in vivo Studies.