Literature DB >> 18225912

3-trifluoromethanesulfonamido-pyrrolidine: a general organocatalyst for anti-selective mannich reactions.

Mickael Pouliquen1, Jérôme Blanchet, Marie-Claire Lasne, Jacques Rouden.   

Abstract

Mannich-type reactions of a glyoxylate imine with carbonyl compounds catalyzed by 3-trifluoromethanesulfonamidopyrrolidine proceed with high yields and anti-stereoselectivity. The catalyst is easily prepared and the transformation appears to be quite general accommodating aldehydes or ketones.

Entities:  

Year:  2008        PMID: 18225912     DOI: 10.1021/ol8000975

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

1.  An organocatalytic route to 2-heteroarylmethylene decorated N-arylpyrroles.

Authors:  Alexandre Jean; Jérôme Blanchet; Jacques Rouden; Jacques Maddaluno; Michaël De Paolis
Journal:  Beilstein J Org Chem       Date:  2013-07-24       Impact factor: 2.883

  1 in total

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