| Literature DB >> 18225753 |
Zeng Yanjun1, Li Guangyu, Fan Bin, Wang Qing, Jie Ving, Liu Aizhen.
Abstract
It was shown that the expression of HIF-1alpha in retinal pigment epithelium increased under hypoxic conditions. Eight hours after the start of hypoxic exposure, the expression of HIF-1alpha reached the peak and sustained after 24-hour hypoxia. However, the morphology of PRE cells began to change and the expression of HIF-1alpha decreased after long-term (48-hour) hypoxia. Hypoxia-induced increase in the level of HIF-1alpha in RPE. It can be an important step in choriodal neovascularization.Entities:
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Year: 2007 PMID： 18225753 DOI： 10.1007/s10517-007-0101-3
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804