Literature DB >> 18224646

Stepwise combinatorial evolution of Akt bisubstrate inhibitors.

Jung Hwan Lee1, Sanjai Kumar, David S Lawrence.   

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Year:  2008        PMID: 18224646     DOI: 10.1002/cbic.200700583

Source DB:  PubMed          Journal:  Chembiochem        ISSN: 1439-4227            Impact factor:   3.164


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  7 in total

1.  Targeting diverse signaling interaction sites allows the rapid generation of bivalent kinase inhibitors.

Authors:  Zachary B Hill; B Gayani K Perera; Simeon S Andrews; Dustin J Maly
Journal:  ACS Chem Biol       Date:  2011-12-22       Impact factor: 5.100

2.  Selection of cyclic-peptide inhibitors targeting Aurora kinase A: problems and solutions.

Authors:  Carolyn D Shomin; Elizabeth Restituyo; Kurt J Cox; Indraneel Ghosh
Journal:  Bioorg Med Chem       Date:  2011-09-29       Impact factor: 3.641

3.  Design and characterization of a potent and selective dual ATP- and substrate-competitive subnanomolar bidentate c-Jun N-terminal kinase (JNK) inhibitor.

Authors:  John L Stebbins; Surya K De; Petra Pavlickova; Vida Chen; Thomas Machleidt; Li-Hsing Chen; Christian Kuntzen; Shinichi Kitada; Michael Karin; Maurizio Pellecchia
Journal:  J Med Chem       Date:  2011-08-23       Impact factor: 7.446

4.  Bivalent inhibitors of the tyrosine kinases ABL and SRC: determinants of potency and selectivity.

Authors:  Zachary B Hill; B Gayani K Perera; Dustin J Maly
Journal:  Mol Biosyst       Date:  2010-11-09

Review 5.  The chemical biology of protein phosphorylation.

Authors:  Mary Katherine Tarrant; Philip A Cole
Journal:  Annu Rev Biochem       Date:  2009       Impact factor: 23.643

6.  Staurosporine tethered peptide ligands that target cAMP-dependent protein kinase (PKA): optimization and selectivity profiling.

Authors:  Carolyn D Shomin; Scott C Meyer; Indraneel Ghosh
Journal:  Bioorg Med Chem       Date:  2009-07-26       Impact factor: 3.641

7.  SRC kinase regulation in progressively invasive cancer.

Authors:  Weichen Xu; Nancy Allbritton; David S Lawrence
Journal:  PLoS One       Date:  2012-11-07       Impact factor: 3.240

  7 in total

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