| Literature DB >> 18223080 |
Hyun Sook Lee1, Yona Cho, Jung-Hyun Lee, Sung Gyun Kang.
Abstract
The TON_0887 gene was identified as the missing histidinol-phosphate phosphatase (HolPase) in the hyperthermophilic archaeon "Thermococcus onnurineus" NA1. The protein contained conserved motifs of the DDDD superfamily of phosphohydrolase, and the recombinantly expressed protein exhibited strong HolPase activity. In this study, we functionally assessed for the first time the monofunctional DDDD-type HolPase, which is organized in the gene cluster.Entities:
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Year: 2008 PMID: 18223080 PMCID: PMC2293174 DOI: 10.1128/JB.01722-07
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490