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Literature DB >> 18222541

Immunology and zebrafish: spawning new models of human disease.

Abstract

The zebrafish has emerged as a powerful new vertebrate model of human disease. Initially prominent in developmental biology, the zebrafish has now been adopted into varied fields of study including immunology. In this review, we describe the characteristics of the zebrafish, which make it a versatile model, including a description of its immune system with its remarkable similarities to its mammalian counterparts. We review the zebrafish disease models of innate and adaptive immunity. Models of immune system malignancies are discussed that are either based on oncogene over-expression or on our own forward-genetic screen that was designed to identify new models of immune dysregulation.

Entities: Disease Species

Mesh：

Year: 2008 PMID： 18222541 DOI： 10.1016/j.dci.2007.11.011

Source DB: PubMed Journal: Dev Comp Immunol ISSN： 0145-305X Impact factor: 3.636

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Cited

111 in total

1. Characterization of mononuclear phagocytic cells in medaka fish transgenic for a cxcr3a:gfp reporter.

Authors: Narges Aghaallaei; Baubak Bajoghli; Heinz Schwarz; Michael Schorpp; Thomas Boehm
Journal: Proc Natl Acad Sci U S A Date: 2010-10-04 Impact factor: 11.205

2. Suppression of Ptf1a activity induces acinar-to-endocrine conversion.

Authors: Daniel Hesselson; Ryan M Anderson; Didier Y R Stainier
Journal: Curr Biol Date: 2011-04-14 Impact factor: 10.834

Review 3. Trolling for the ideal model host: zebrafish take the bait.

Authors: Jonathan P Allen; Melody N Neely
Journal: Future Microbiol Date: 2010-04 Impact factor: 3.165

4. Burkholderia cenocepacia creates an intramacrophage replication niche in zebrafish embryos, followed by bacterial dissemination and establishment of systemic infection.

Authors: Annette C Vergunst; Annemarie H Meijer; Stephen A Renshaw; David O'Callaghan
Journal: Infect Immun Date: 2010-01-19 Impact factor: 3.441

Review 5. Insights into early mycobacterial pathogenesis from the zebrafish.

Authors: Robin Lesley; Lalita Ramakrishnan
Journal: Curr Opin Microbiol Date: 2008-06-19 Impact factor: 7.934

6. Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish.

Authors: Britton C Goodale; Susan C Tilton; Margaret M Corvi; Glenn R Wilson; Derek B Janszen; Kim A Anderson; Katrina M Waters; Robert L Tanguay
Journal: Toxicol Appl Pharmacol Date: 2013-05-05 Impact factor: 4.219

Immunology and zebrafish: spawning new models of human disease.

1. Characterization of mononuclear phagocytic cells in medaka fish transgenic for a cxcr3a:gfp reporter.

2. Suppression of Ptf1a activity induces acinar-to-endocrine conversion.

Review 3. Trolling for the ideal model host: zebrafish take the bait.

4. Burkholderia cenocepacia creates an intramacrophage replication niche in zebrafish embryos, followed by bacterial dissemination and establishment of systemic infection.

Review 5. Insights into early mycobacterial pathogenesis from the zebrafish.

6. Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish.

7. Non-invasive imaging of disseminated candidiasis in zebrafish larvae.

8. Yeast and Filaments Have Specialized, Independent Activities in a Zebrafish Model of Candida albicans Infection.

Review 9. Viral diseases in zebrafish: what is known and unknown.

10. Characterization of the zebrafish T cell receptor beta locus.