| Literature DB >> 18220403 |
Kerri L Jones1, Achim Porzelle, Adrian Hall, Michael D Woodrow, Nicholas C O Tomkinson.
Abstract
An efficient method for the copper-catalyzed N-arylation of hydroxylamines with aryl iodides is described. A variety of N- and O-functionalized hydroxylamines were transformed in good to excellent yield with a broad range of aryl coupling partners. Methods for the selective deprotection of either the N- or O-substituents for further functionalization are also described.Entities:
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Year: 2008 PMID: 18220403 DOI: 10.1021/ol7029273
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005