BACKGROUND: The neonatal multiple organ dysfunction score (NEOMOD) predicts mortality during the first 28 days of life, and provides information on organ functions influencing mortality. AIM: To test the predictive and descriptive accuracy of NEOMOD in very low birth weight (VLBW) infants. METHODS: The system was used in 112 infants. It evaluates the central nervous system (CNS), coagulation, respiratory, gastrointestinal (GIT), cardiovascular (CVS), renal system, and acid-base balance in 24-h intervals during the first 28 days of life. RESULTS: A NEOMOD of > or =9 was associated with 100% mortality. A receiver operating characteristic (ROC) curve was used for assessing the accuracy of NEOMOD score in prediction of mortality. The area under curve (AUC) attained by NEOMOD was 0.93 for mortality. CONCLUSIONS: The NEOMOD evaluates daily the severity of the multiple organ dysfunction syndrome (MODS) and is an accurate predictor of mortality.
BACKGROUND: The neonatal multiple organ dysfunction score (NEOMOD) predicts mortality during the first 28 days of life, and provides information on organ functions influencing mortality. AIM: To test the predictive and descriptive accuracy of NEOMOD in very low birth weight (VLBW) infants. METHODS: The system was used in 112 infants. It evaluates the central nervous system (CNS), coagulation, respiratory, gastrointestinal (GIT), cardiovascular (CVS), renal system, and acid-base balance in 24-h intervals during the first 28 days of life. RESULTS: A NEOMOD of > or =9 was associated with 100% mortality. A receiver operating characteristic (ROC) curve was used for assessing the accuracy of NEOMOD score in prediction of mortality. The area under curve (AUC) attained by NEOMOD was 0.93 for mortality. CONCLUSIONS: The NEOMOD evaluates daily the severity of the multiple organ dysfunction syndrome (MODS) and is an accurate predictor of mortality.
Authors: Stéphane Leteurtre; Alain Martinot; Alain Duhamel; François Proulx; Bruno Grandbastien; Jacques Cotting; Ronald Gottesman; Ari Joffe; Jurg Pfenninger; Philippe Hubert; Jacques Lacroix; Francis Leclerc Journal: Lancet Date: 2003-07-19 Impact factor: 79.321
Authors: Nawar Bestati; Stéphane Leteurtre; Alain Duhamel; François Proulx; Bruno Grandbastien; Jacques Lacroix; Francis Leclerc Journal: Crit Care Date: 2010-11-09 Impact factor: 9.097