Literature DB >> 1821909

[Hepatic fascioliasis. Uncommon cause of prolonged febrile syndrome with hypereosinophilia and hypodense images on computed tomography of the liver].

M Melero1, R C Rigou, J Lloveras, O Gennaro.   

Abstract

A 40 year old man was admitted with prolonged fever, hypereosinophilia, increased serum levels of cholestasis enzymes and low density masses in the hepatic computed tomography (CT). A liver needle biopsy was performed under CT control. Neoplastic, pyogenic or amoebic etiology were excluded. Stool parasitologic examination was also negative. A diagnosis of hepatic fasciolasis was based on the finding of operculate eggs in duodenal juice obtained by duodenal aspiration. The patient was successfully treated with triclabendazole (10/mg/kg/single dose). The purpose of this communication is to emphasize 1) that prolonged fever with hypereosinophilia and focal lesions in hepatic CT suggest the presence of fasciola hepatica which must be investigated particularly in duodenal juice; 2) the CT aspects of this disease; 3) that triclabendazole, a benzimidazolic compound, is a new therapeutic possibility acting on immature and adult forms of the parasite in the liver.

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Year:  1991        PMID: 1821909

Source DB:  PubMed          Journal:  Medicina (B Aires)        ISSN: 0025-7680            Impact factor:   0.653


  1 in total

Review 1.  Human fascioliasis in Argentina: retrospective overview, critical analysis and baseline for future research.

Authors:  Roberto Mera y Sierra; Veronica H Agramunt; Pablo Cuervo; Santiago Mas-Coma
Journal:  Parasit Vectors       Date:  2011-06-11       Impact factor: 3.876

  1 in total

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