Literature DB >> 18219061

Review on diagnosis and treatment of focal segmental glomerulosclerosis.

J K J Deegens1, E J Steenbergen, J F M Wetzels.   

Abstract

Focal segmental glomerulosclerosis (FSGS) is one the most important causes of the nephrotic syndrome in adult patients. FSGS is not a disease entity. The identification of underlying causes of FSGS (secondary FSGS) has increased our insight into the pathogenesis of FSGS. Moreover, differentiating between primary (idiopathic) and secondary forms of FSGS is important to allow appropriate treatment. Recently a new pathological classification of FSGS was proposed, expanding FSGS to include nonsclerotic lesions. In this review we discuss the current diagnostic and therapeutic options in patients with FSGS.

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Year:  2008        PMID： 18219061

Source DB:  PubMed          Journal:  Neth J Med        ISSN： 0300-2977            Impact factor:   1.422


  12 in total

1.  Open-Label Clinical Trials of Oral Pulse Dexamethasone for Adults with Idiopathic Nephrotic Syndrome.

Authors:  Monique E Cho; Mary H Branton; David A Smith; Linda Bartlett; Lilian Howard; James C Reynolds; Donald Rosenstein; Sanjeev Sethi; M Berenice Nava; Laura Barisoni; Fernando C Fervenza; Jeffrey B Kopp
Journal:  Am J Nephrol       Date:  2019-04-09       Impact factor: 3.754

2.  Janus kinase 2/signal transducer and activator of transcription 3 inhibitors attenuate the effect of cardiotrophin-like cytokine factor 1 and human focal segmental glomerulosclerosis serum on glomerular filtration barrier.

Authors:  Mukut Sharma; Jianping Zhou; Jean-François Gauchat; Ram Sharma; Ellen T McCarthy; Tarak Srivastava; Virginia J Savin
Journal:  Transl Res       Date:  2015-03-16       Impact factor: 7.012

Review 3.  Minimal change disease and idiopathic FSGS: manifestations of the same disease.

Authors:  Rutger J Maas; Jeroen K Deegens; Bart Smeets; Marcus J Moeller; Jack F Wetzels
Journal:  Nat Rev Nephrol       Date:  2016-10-17       Impact factor: 28.314

4.  The role of renin angiotensin system inhibition in kidney repair.

Authors:  Irene M van der Meer; Paolo Cravedi; Giuseppe Remuzzi
Journal:  Fibrogenesis Tissue Repair       Date:  2010-05-04

5.  Frequency and clinicopathological characteristics of variants of primary focal segmental glomerulosclerosis in adults presenting with nephrotic syndrome.

Authors:  Shaheera Shakeel; Muhammed Mubarak; Javed I Kazi; Nazrul Jafry; Ejaz Ahmed
Journal:  J Nephropathol       Date:  2013-01-01

Review 6.  Serum suPAR in patients with FSGS: trash or treasure?

Authors:  Rutger J H Maas; Jeroen K J Deegens; Jack F M Wetzels
Journal:  Pediatr Nephrol       Date:  2013-03-21       Impact factor: 3.714

7.  Targeting mTOR Signaling Can Prevent the Progression of FSGS.

Authors:  Stefan Zschiedrich; Tillmann Bork; Wei Liang; Nicola Wanner; Kristina Eulenbruch; Stefan Munder; Björn Hartleben; Oliver Kretz; Simon Gerber; Matias Simons; Amandine Viau; Martine Burtin; Changli Wei; Jochen Reiser; Nadja Herbach; Maria-Pia Rastaldi; Clemens D Cohen; Pierre-Louis Tharaux; Fabiola Terzi; Gerd Walz; Markus Gödel; Tobias B Huber
Journal:  J Am Soc Nephrol       Date:  2017-03-07       Impact factor: 10.121

8.  A retrospective study of focal segmental glomerulosclerosis: clinical criteria can identify patients at high risk for recurrent disease after first renal transplantation.

Authors:  Rutger J H Maas; Jeroen K J Deegens; Jan A J G van den Brand; Elisabeth A M Cornelissen; Jack F M Wetzels
Journal:  BMC Nephrol       Date:  2013-02-22       Impact factor: 2.388

9.  Urinary IgG and α2-macroglobulin are powerful predictors of outcome and responsiveness to steroids and cyclophosphamide in idiopathic focal segmental glomerulosclerosis with nephrotic syndrome.

Authors:  Claudio Bazzi; Virginia Rizza; Daniela Casellato; Gilda Stivali; Gregorio Rachele; Pietro Napodano; Maurizio Gallieni; Giuseppe D'Amico
Journal:  Biomed Res Int       Date:  2013-09-04       Impact factor: 3.411

10.  Balance between the two kinin receptors in the progression of experimental focal and segmental glomerulosclerosis in mice.

Authors:  Rafael Luiz Pereira; Raphael José Ferreira Felizardo; Marcos Antônio Cenedeze; Meire Ioshie Hiyane; Enio José Bassi; Mariane Tami Amano; Clarice Sylvia Taemi Origassa; Reinaldo Correia Silva; Cristhiane Fávero Aguiar; Sylvia Mendes Carneiro; João Bosco Pesquero; Ronaldo Carvalho Araújo; Alexandre de Castro Keller; Renato C Monteiro; Ivan Cruz Moura; Alvaro Pacheco-Silva; Niels Olsen Saraiva Câmara
Journal:  Dis Model Mech       Date:  2014-04-17       Impact factor: 5.758
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