Literature DB >> 1821686

Recent advances in dystrophin research.

C V Rojas1, E P Hoffman.   

Abstract

Evidence suggesting that dystrophin is a component of the membrane cytoskeleton of excitable cells continues to accumulate. Whereas the specific mechanisms leading to muscle pathology in Duchenne muscular dystrophy are still being debated it is apparent that the progressive weakness that occurs in this disease is the result of a chronic process that is initiated by dystrophin deficiency.

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Year:  1991        PMID: 1821686     DOI: 10.1016/0959-4388(91)90064-e

Source DB:  PubMed          Journal:  Curr Opin Neurobiol        ISSN: 0959-4388            Impact factor:   6.627


  6 in total

1.  The basal lamina is a physical barrier to herpes simplex virus-mediated gene delivery to mature muscle fibers.

Authors:  J Huard; W G Feero; S C Watkins; E P Hoffman; D J Rosenblatt; J C Glorioso
Journal:  J Virol       Date:  1996-11       Impact factor: 5.103

2.  Enhanced sensitivity of hippocampal pyramidal neurons from mdx mice to hypoxia-induced loss of synaptic transmission.

Authors:  M F Mehler; K Z Haas; J A Kessler; P K Stanton
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-15       Impact factor: 11.205

3.  Proteolysis results in altered leak channel kinetics and elevated free calcium in mdx muscle.

Authors:  P R Turner; R Schultz; B Ganguly; R A Steinhardt
Journal:  J Membr Biol       Date:  1993-05       Impact factor: 1.843

4.  Tissue specific expression of an alpha-skeletal actin-lacZ fusion gene during development in transgenic mice.

Authors:  E A Asante; J M Boswell; D W Burt; G Bulfield
Journal:  Transgenic Res       Date:  1994-01       Impact factor: 2.788

5.  Heterokaryon myotubes with normal mouse and Duchenne nuclei exhibit sarcolemmal dystrophin staining and efficient intracellular free calcium control.

Authors:  W F Denetclaw; G Bi; D V Pham; R A Steinhardt
Journal:  Mol Biol Cell       Date:  1993-09       Impact factor: 4.138

6.  Direct visualization of the dystrophin network on skeletal muscle fiber membrane.

Authors:  V Straub; R E Bittner; J J Léger; T Voit
Journal:  J Cell Biol       Date:  1992-12       Impact factor: 10.539

  6 in total

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