Literature DB >> 18215427

Comparison of immunofluorescence assay and multiplexed microparticle-based immunoassay for detecting Epstein-Barr virus viral capsid antigen antibodies.

Aysin Zeytinoglu1, Imre Altuglu, Eylem Karatas, Ruchan Yazan Sertoz.   

Abstract

A new multiplexed microparticle-based immunoassay was compared with the immunofluorescence assay that is used widely for detecting EBV-specific antibodies in immunocompetent patients. Serum samples of 162 patients submitted for routine EBV diagnosis were tested for viral capsid antigen IgM, viral capsid antigen IgG and serological profile interpretations with both systems. The result concordances were 94.2%, 93.6%, and 92.1%, respectively. Multiplexed microparticle-based immunoassay can be an alternative to immunofluorescence assay especially in laboratories receiving large numbers of samples.

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Year:  2008        PMID: 18215427     DOI: 10.1016/j.jviromet.2007.12.001

Source DB:  PubMed          Journal:  J Virol Methods        ISSN: 0166-0934            Impact factor:   2.014


  3 in total

1.  Performance of new enzyme-linked fluorescent assays for detection of Epstein-Barr virus specific antibodies in routine diagnostics.

Authors:  Christoph Koidl; Regina Riedl; Bettina Schweighofer; Sandra Fett; Michael Bozic; Egon Marth
Journal:  Wien Klin Wochenschr       Date:  2011-03-31       Impact factor: 1.704

2.  Evidence-based approach for interpretation of Epstein-Barr virus serological patterns.

Authors:  J S Klutts; B A Ford; N R Perez; A M Gronowski
Journal:  J Clin Microbiol       Date:  2009-08-05       Impact factor: 5.948

Review 3.  Laboratory assays for Epstein-Barr virus-related disease.

Authors:  Margaret L Gulley; Weihua Tang
Journal:  J Mol Diagn       Date:  2008-06-13       Impact factor: 5.568

  3 in total

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