BACKGROUND: Accurate diagnosis of hepatic vein (HV) stenosis by real-time and color Doppler US (CD-US) after segmental liver transplantation in children can decrease morbidity because it allows unnecessary biopsy, obstruction or thrombosis and loss of the graft to be avoided. OBJECTIVE: To evaluate CD-US parameters to predict HV stenosis after segmental liver transplantation in children. MATERIALS AND METHODS: Retrospective review of 79 CD-US examinations measuring velocity at the HV anastomosis (HV1) and the main trunk 1-2 cm proximal to the HV/IVC anastomosis (HV2), the HV1/HV2 ratio and the spectral waveform of HV2. The study group comprised patients with stenosis confirmed by angiography. The control group comprised patients with a good clinical outcome. RESULTS: HV stenosis was seen in 12 CD-US examinations. The mean HV1/HV2 ratio was higher in the study group (6.0 versus 4.0). An HV1/HV2 ratio of >4.1 was predictive of HV stenosis (sensitivity 83%, specificity 76%). CONCLUSION: An HV1/HV2 ratio of >4.1 is a highly predictive CD-US parameter for the detection of hemodynamically significant HV stenosis on angiography.
BACKGROUND: Accurate diagnosis of hepatic vein (HV) stenosis by real-time and color Doppler US (CD-US) after segmental liver transplantation in children can decrease morbidity because it allows unnecessary biopsy, obstruction or thrombosis and loss of the graft to be avoided. OBJECTIVE: To evaluate CD-US parameters to predict HV stenosis after segmental liver transplantation in children. MATERIALS AND METHODS: Retrospective review of 79 CD-US examinations measuring velocity at the HV anastomosis (HV1) and the main trunk 1-2 cm proximal to the HV/IVC anastomosis (HV2), the HV1/HV2 ratio and the spectral waveform of HV2. The study group comprised patients with stenosis confirmed by angiography. The control group comprised patients with a good clinical outcome. RESULTS:HV stenosis was seen in 12 CD-US examinations. The mean HV1/HV2 ratio was higher in the study group (6.0 versus 4.0). An HV1/HV2 ratio of >4.1 was predictive of HV stenosis (sensitivity 83%, specificity 76%). CONCLUSION: An HV1/HV2 ratio of >4.1 is a highly predictive CD-US parameter for the detection of hemodynamically significant HV stenosis on angiography.
Authors: U Settmacher; N C Nüssler; M Glanemann; R Haase; M Heise; W O Bechstein; P Neuhaus Journal: Clin Transplant Date: 2000-06 Impact factor: 2.863
Authors: Joseph F Buell; Brian Funaki; David C Cronin; Atsushi Yoshida; Meryl K Perlman; Jonathan Lorenz; Sue Kelly; Lynda Brady; Jeffrey A Leef; J Michael Millis Journal: Ann Surg Date: 2002-11 Impact factor: 12.969
Authors: T L Huang; T Y Chen; L L Tsang; P L Sun; Y S Chen; C C Wang; S H Wang; T S Lin; Y C Chiang; K W Chiu; H L Eng; B Jawan; Y F Cheng; C L Chen Journal: Transplant Proc Date: 2004-10 Impact factor: 1.066
Authors: J A Goss; C R Shackleton; S V McDiarmid; M Maggard; K Swenson; P Seu; J Vargas; M Martin; M Ament; J Brill; R Harrison; R W Busuttil Journal: Ann Surg Date: 1998-09 Impact factor: 12.969
Authors: A B Zajko; D Claus; P Clapuyt; C O Esquivel; D Moulin; T E Starzl; J de Ville de Goyet; J B Otte Journal: Radiology Date: 1989-03 Impact factor: 11.105