Literature DB >> 18214318

Evaluation of psychoemotional status of rats after brain injury and systemic transplantation of mesenchymal stem cells.

A F Tsyb1, L M Roshal, A G Konoplyannikov, G N Souchkevitch, Yu G Verkhovskii, A S Shevchuk, L N Pavlova, L P Zhavoronkov, J B Semenova, V V Yuzhakov, O I Kolganova, G A Lushnikova, E P Ananyeva.   

Abstract

We studied the effects of systemic transplantation of mesenchymal stem cells obtained after culturing of autologous bone marrow on psychophysiological status of Wistar rats after diffuse brain trauma. Two months after systemic injection of mesenchymal stem cells we observed a decrease in manifestations of emotional behavioral reactions (anxiety and excitability) and shortening of the time of realization of drinking behavior in a T-maze. A significant positive effect of systemic transfusion of mesenchymal stem cells on avoidance conditioning in a shuttle box was observed 3 months after brain injury.

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Year:  2007        PMID: 18214318     DOI: 10.1007/s10517-007-0174-z

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  2 in total

Review 1.  Mechanisms supporting potential use of bone marrow-derived mesenchymal stem cells in psychocardiology.

Authors:  Jianyang Liu; Lijun Zhang; Meiyan Liu
Journal:  Am J Transl Res       Date:  2019-11-15       Impact factor: 4.060

2.  Transplantation of autologous bone marrow-derived mesenchymal stem cells for traumatic brain injury.

Authors:  Jindou Jiang; Xingyao Bu; Meng Liu; Peixun Cheng
Journal:  Neural Regen Res       Date:  2012-01-05       Impact factor: 5.135

  2 in total

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