| Literature DB >> 18214318 |
A F Tsyb1, L M Roshal, A G Konoplyannikov, G N Souchkevitch, Yu G Verkhovskii, A S Shevchuk, L N Pavlova, L P Zhavoronkov, J B Semenova, V V Yuzhakov, O I Kolganova, G A Lushnikova, E P Ananyeva.
Abstract
We studied the effects of systemic transplantation of mesenchymal stem cells obtained after culturing of autologous bone marrow on psychophysiological status of Wistar rats after diffuse brain trauma. Two months after systemic injection of mesenchymal stem cells we observed a decrease in manifestations of emotional behavioral reactions (anxiety and excitability) and shortening of the time of realization of drinking behavior in a T-maze. A significant positive effect of systemic transfusion of mesenchymal stem cells on avoidance conditioning in a shuttle box was observed 3 months after brain injury.Entities:
Mesh:
Year: 2007 PMID: 18214318 DOI: 10.1007/s10517-007-0174-z
Source DB: PubMed Journal: Bull Exp Biol Med ISSN: 0007-4888 Impact factor: 0.804