Literature DB >> 18212111

Effect of 14-membered-ring macrolides on production of interleukin-8 mediated by protease-activated receptor 2 in human keratinocytes.

Tatsuya Tsuda1, Chika Ishikawa, Hiroe Konishi, Yoshiaki Hayashi, Noboru Nakagawa, Masato Matsuki, Hitoshi Mizutani, Kiyofumi Yamanishi.   

Abstract

The production of interleukin-8 induced by the activation of protease-activated receptor 2 and its synergism with interleukin-1beta were modulated by 14-membered-ring macrolides, namely, roxithromycin, erythromycin, and clarithromycin, in cultured normal human epidermal keratinocytes. Those macrolides may attenuate the protease-activated receptor 2-interleukin-8 axis and thereby modulate proinflammatory responses in the skin.

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Year:  2008        PMID： 18212111      PMCID： PMC2292555          DOI： 10.1128/AAC.00140-07

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  23 in total

1.  [Therapeutic effects of macrolides on patients with psoriasis vulgaris, pigmentary prurigo, or eosinophilic pustule folliculitis].

Authors:  N Komiya; K Tamaoki
Journal:  Jpn J Antibiot       Date:  2001-02

2.  The successful treatment of prurigo pigmentosa with macrolide antibiotics.

Authors:  N Yazawa; H Ihn; K Yamane; T Etoh; K Tamaki
Journal:  Dermatology       Date:  2001       Impact factor: 5.366

Review 3.  Anti-inflammatory capabilities of macrolides.

Authors:  J Zalewska-Kaszubska; D Górska
Journal:  Pharmacol Res       Date:  2001-12       Impact factor: 7.658

4.  The penetration of roxithromycin into human skin.

Authors:  M Campa; I Zolfino; S Senesi; N Bernardini; R Danesi; M Ducci; M Oleggini; R Di Stefano; F Mosca; A Lazzarini
Journal:  J Antimicrob Chemother       Date:  1990-07       Impact factor: 5.790

5.  Macrolide antibiotics promote the LPS-induced upregulation of prostaglandin E receptor EP2 and thus attenuate macrolide suppression of IL-6 production.

Authors:  Yoshinori Sato; Kenichi Kaneko; Matsuhisa Inoue
Journal:  Prostaglandins Leukot Essent Fatty Acids       Date:  2007-02-26       Impact factor: 4.006

6.  Effects of macrolides on interleukin-8 secretion from human nasal epithelial cells.

Authors:  K Fujita; T Shimizu; Y Majima; Y Sakakura
Journal:  Eur Arch Otorhinolaryngol       Date:  2000       Impact factor: 2.503

7.  Proinflammatory role of proteinase-activated receptor-2 in humans and mice during cutaneous inflammation in vivo.

Authors:  Stephan Seeliger; Cllaudia K Derian; Nathalie Vergnolle; Nigel W Bunnett; Roman Nawroth; Martin Schmelz; Pierre-Yves Von Der Weid; Jörg Buddenkotte; Cord Sunderkötter; Dieter Metze; Patricia Andrade-Gordon; Erik Harms; Dietmar Vestweber; Thomas A Luger; Martin Steinhoff
Journal:  FASEB J       Date:  2003-10       Impact factor: 5.191

8.  Human airway trypsin-like protease induces PAR-2-mediated IL-8 release in psoriasis vulgaris.

Authors:  Kana Iwakiri; Mohammad Ghazizadeh; Enjing Jin; Masakazu Fujiwara; Tamiko Takemura; Shin-ichiro Takezaki; Seiji Kawana; Susumu Yasuoka; Oichi Kawanami
Journal:  J Invest Dermatol       Date:  2004-04       Impact factor: 8.551

Review 9.  Immunopathogenesis of psoriasis.

Authors:  Maki Ozawa; Setsuya Aiba
Journal:  Curr Drug Targets Inflamm Allergy       Date:  2004-06

10.  Erythromycin ethyl succinate: diffusion through interstitial dermal fluid.

Authors:  L Vaillant; G Lorette; J Loulergue; A Audurier
Journal:  Eur J Clin Pharmacol       Date:  1987       Impact factor: 2.953
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  2 in total

1.  Tetracyclines modulate protease-activated receptor 2-mediated proinflammatory reactions in epidermal keratinocytes.

Authors:  Chika Ishikawa; Tatsuya Tsuda; Hiroe Konishi; Noboru Nakagawa; Kiyofumi Yamanishi
Journal:  Antimicrob Agents Chemother       Date:  2009-03-02       Impact factor: 5.191

2.  Chronic mandibular osteomyelitis with suspected underlying synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome: a case report.

Authors:  Yumi Mochizuki; Ken Omura; Hideaki Hirai; Takuma Kugimoto; Toshimitu Osako; Takahide Taguchi
Journal:  J Inflamm Res       Date:  2012-02-27
  2 in total

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