Literature DB >> 18211488

Acromegaly presenting as cutis verticis gyrata.

Mohammad Al-Bedaia1, And Sultan Al-Khenaizan.   

Abstract

A 17-year-old Saudi male patient presented with progressive asymptomatic skin changes on the scalp for 4 years. Upon examination, he was a well-built muscular male with coarse facial features with broadening of the nasal bridge and thick lips. Scalp examination revealed multiple gyriform oblong skin folds in the fronto-parietal region (Fig. 1). Extensive velvety dark brown plaques were seen on sides of the neck, axillae, and groin. Similar eruption was seen on the knuckles of both hands and around the eyes. Clinical diagnosis of cutis verticis gyrata of the scalp and acanthosis nigricans was made. Because of the extent and the rapid progression of the above changes, acromegaly was suspected. Endocrinology referral confirmed this by the findings of high random growth hormone level at the value of 37.3 mIU/L (normal 0.2-13.0). Arrangement of magnetic resonance imaging (MRI) of the brain was made, but unfortunately the patient was lost to follow-up.

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Year:  2008        PMID: 18211488     DOI: 10.1111/j.1365-4632.2008.03350.x

Source DB:  PubMed          Journal:  Int J Dermatol        ISSN: 0011-9059            Impact factor:   2.736


  3 in total

Review 1.  Acromegaly: clinical features at diagnosis.

Authors:  Lucio Vilar; Clarice Freitas Vilar; Ruy Lyra; Raissa Lyra; Luciana A Naves
Journal:  Pituitary       Date:  2017-02       Impact factor: 4.107

2.  Cerebriform intradermal nevus presenting as cutis verticis gyrata with multiple cellular blue nevus over the body: A rare occurrence.

Authors:  Somenath Sarkar; Soumyajit Roychoudhury; Arpit Shrimal; Kapildeb Das
Journal:  Indian Dermatol Online J       Date:  2014-01

Review 3.  Cutis verticis gyrata: a cutaneous finding in acromegaly.

Authors:  Giullia Menuci Chianca Landenberger; Bárbara Roberta Ongaratti; Júlia Fernanda Semmelmann Pereira-Lima; Miriam da Costa Oliveira
Journal:  An Bras Dermatol       Date:  2022-03-11       Impact factor: 2.113

  3 in total

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