Literature DB >> 18211258

Conception without the development of a human being.

Erik E Hauzman1, Zoltán Papp.   

Abstract

Conception sometimes results in products that are not capable of developing into an embryo and fetus. This group, designated with the term gestational trophoblastic neoplasia, comprises the benign hydatidiform mole, the invasive mole (chorioadenoma destruens) and the frankly malignant variety, choriocarcinoma. Another type of atypical oocyte activation occurs in parthenogenesis. In the human, two types of tumors, dermoid cysts and teratomas, are believed to result from this process. We elucidate the generation of these abnormal growths and provide explanations as to why they cannot be regarded as human individuals or human beings. We argue that it is not the number of chromosomes that is required for a given form of human life to become a human being but rather the biparental origin of the chromosome set.

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Year:  2008        PMID: 18211258     DOI: 10.1515/JPM.2008.028

Source DB:  PubMed          Journal:  J Perinat Med        ISSN: 0300-5577            Impact factor:   1.901


  2 in total

1.  Patenting parthenotes in the US and Europe.

Authors:  Vincenzo Senatore; Christopher Thomas Scott; Vittorio Sebastiano
Journal:  Nat Biotechnol       Date:  2015-12-09       Impact factor: 54.908

2.  Dysregulation of Placental Functions and Immune Pathways in Complete Hydatidiform Moles.

Authors:  Jennifer R King; Melissa L Wilson; Szabolcs Hetey; Peter Kiraly; Koji Matsuo; Antonio V Castaneda; Eszter Toth; Tibor Krenacs; Petronella Hupuczi; Paulette Mhawech-Fauceglia; Andrea Balogh; Andras Szilagyi; Janos Matko; Zoltan Papp; Lynda D Roman; Victoria K Cortessis; Nandor Gabor Than
Journal:  Int J Mol Sci       Date:  2019-10-10       Impact factor: 5.923

  2 in total

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