Literature DB >> 18209679

High prevalence of gonococcal and chlamydial infection in men who have sex with men with newly diagnosed HIV infection: an opportunity for same-day presumptive treatment.

Katherine C Scott1, Susan Philip, Katherine Ahrens, Charlotte K Kent, Jeffrey D Klausner.   

Abstract

BACKGROUND: The increasing use of point-of-care HIV tests in sexually transmitted disease (STD) clinics allows for rapid identification of patients with newly diagnosed HIV infection who may also be at risk for more common sexually transmitted infections. Positive point-of-care HIV test results might be used to identify and provide presumptive treatment to patients who are likely to be coinfected with gonorrhea (GC) and chlamydia (CT).
METHODS: Data from 6864 STD clinic visits by men who have sex with men (MSM) with no history of HIV infection and an HIV antibody test at that visit were analyzed. Results from rectal, pharyngeal, and urine nucleic acid amplification tests were used to calculate the prevalence of infection with GC and CT.
RESULTS: MSM with newly diagnosed HIV infection were more likely than HIV-uninfected MSM to be infected with GC (25.9% [53 of 205] vs. 10.9% [728 of 6659]; P < 0.001) and CT (18.5% [38 of 205] vs. 7.8% [518 of 6659]; P < 0.001).
CONCLUSIONS: GC and CT are common in MSM with newly diagnosed HIV infection at an STD clinic. In this population, a positive point-of-care HIV test result is a useful risk marker for untreated gonococcal and chlamydial infections and provides a justification for presumptive GC and CT treatment.

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Year:  2008        PMID: 18209679     DOI: 10.1097/QAI.0b013e318165dc0b

Source DB:  PubMed          Journal:  J Acquir Immune Defic Syndr        ISSN: 1525-4135            Impact factor:   3.731


  12 in total

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2.  Accuracy of Presumptive Gonorrhea Treatment for Gay, Bisexual, and Other Men Who Have Sex with Men: Results from a Large Sexual Health Clinic in Los Angeles, California.

Authors:  Chelsea L Shover; Matthew R Beymer; Erin M Unger; Marjan Javanbakht; Robert K Bolan
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4.  New Human Immunodeficiency Virus Diagnosis Independently Associated With Rectal Gonorrhea and Chlamydia in Men Who Have Sex With Men.

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8.  Adolescent sexually transmitted infections and risk for subsequent HIV.

Authors:  E Claire Newbern; Greta L Anschuetz; Michael G Eberhart; Melinda E Salmon; Kathleen A Brady; Andrew De Los Reyes; Jane M Baker; Lenore E Asbel; Caroline C Johnson; Donald F Schwarz
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9.  Hydrogen peroxide-producing lactobacilli inhibit gonococci in vitro but not during experimental genital tract infection.

Authors:  Dawn F Muench; David J Kuch; Hong Wu; Afrin A Begum; Sandra J Veit; Marie-Eve Pelletier; Angel A Soler-García; Ann E Jerse
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10.  Syphilis predicts HIV incidence among men and transgender women who have sex with men in a preexposure prophylaxis trial.

Authors:  Marc M Solomon; Kenneth H Mayer; David V Glidden; Albert Y Liu; Vanessa M McMahan; Juan V Guanira; Suwat Chariyalertsak; Telmo Fernandez; Robert M Grant
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