Literature DB >> 182091

Effects of steriod hormones on human fibroblasts in vitro. II. Antagonism by androgens of cortisol-induced inhibition.

W Harvey, R Grahame, G S Panayi.   

Abstract

Inhibition of dermal activity by cortisol in culture was partially reversed by two naturally occurring androgens, testosterone and dihydrotestosterone. ACTH and the androgen precursor dehydroepiandrosterone sulphate showed not such antagonistic effect. These results suggest that increased production of adrenal androgens during ACTH therapy may account for the relative absnece of 'skin-thinning' and 'steroid-bruising' which are common side-effects of corticosteroid therapy.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 182091      PMCID： PMC1006526          DOI： 10.1136/ard.35.2.148

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  14 in total

1.  Corticosteroid bruising.

Authors:  H F WEST
Journal:  Ann Rheum Dis       Date:  1961-03       Impact factor: 19.103

Review 2.  Androgen production and metabolism in normal and virilized women.

Authors:  M A Kirschner; C W Bardin
Journal:  Metabolism       Date:  1972-07       Impact factor: 8.694

3.  Specific glucocorticoid-binding macromolecules from mouse fibroblasts growing in vitro. A possible steroid receptor for growth inhibition.

Authors:  J F Hackney; S R Gross; L Aronow; W B Pratt
Journal:  Mol Pharmacol       Date:  1970-09       Impact factor: 4.436

4.  Elasticity of human skin in vivo. A study of the physical properties of the skin in rheumatoid arthritis and the effect of corticosteroids.

Authors:  R Grahame
Journal:  Ann Phys Med       Date:  1969-08

5.  Effects of steroid hormones on human fibroblasts in vitro. I. Glucocorticoid action on cell growth and collagen synthesis.

Authors:  W Harvey; R Grahame; G S Panayi
Journal:  Ann Rheum Dis       Date:  1974-09       Impact factor: 19.103

Review 6.  Recent studies on the mechanism of action of testosterone.

Authors:  J D Wilson
Journal:  N Engl J Med       Date:  1972-12-21       Impact factor: 91.245

7.  Corticosteroid-induced inhibition of the biosynthesis of human skin collagen.

Authors:  J Uitto; H Teir; K K Mustakallio
Journal:  Biochem Pharmacol       Date:  1972-08-15       Impact factor: 5.858

8.  The metabolism of testosterone by skin in normal subjects and in testicular feminization.

Authors:  J S Jenkins; S Ash
Journal:  J Endocrinol       Date:  1971-03       Impact factor: 4.286

9.  Interaction between catabolic and anabolic steroids.

Authors:  K Little
Journal:  Curr Ther Res Clin Exp       Date:  1970-10

10.  Some mechanisms of action of stanozolol (stromba) and its interaction with cortisone.

Authors:  K Little; L Munuera
Journal:  Curr Ther Res Clin Exp       Date:  1970-05
View more
  2 in total

1.  Polarization microscopy of picrosirius red-stained collagen from oxodipine-induced hyperplastic gingiva of beagle dogs.

Authors:  D Dayan; T Waner; H Tal; A Nyska
Journal:  Int J Exp Pathol       Date:  1993-06       Impact factor: 1.925

2.  Human Dermal Fibroblast: A Promising Cellular Model to Study Biological Mechanisms of Major Depression and Antidepressant Drug Response.

Authors:  Pierre Mesdom; Romain Colle; Elise Lebigot; Séverine Trabado; Eric Deflesselle; Bruno Fève; Laurent Becquemont; Emmanuelle Corruble; Céline Verstuyft
Journal:  Curr Neuropharmacol       Date:  2020       Impact factor: 7.363
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.