[Melkersson-Rosenthal syndrome treated with clofazimine].

Melkersson-Rosenthal syndrome (MRS) is a triad of facial palsy, lingua plicata and chronic orofacial swelling. Mono- and oligosymptomatic forms are common and cheilitis granulomatosa is often considered a monosymptomatic form of MRS. In advanced stages the histological findings are noncaseating granulomas. The etiology remains unclear and treatment is difficult. A few uncontrolled studies have shown corticosteroids and clofazimine to be effective. We report on a 31 year-old man with complete MRS who responded well to treatment with clofazimine.