Literature DB >> 1820865

Role of surfactants in the bioavailability of intranasal insulin.

A Sanchez1, P Ygartua, D Fos.   

Abstract

The nasal mucosa has good physiological characteristics to allow the administration through other routes presents some problems, such is the case of insulin. The presence of surfactants is necessary to get high bioavailability.

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Year:  1991        PMID: 1820865

Source DB:  PubMed          Journal:  Eur J Drug Metab Pharmacokinet        ISSN: 0378-7966            Impact factor:   2.441


  1 in total

1.  Insulin containing nanocomplexes formed by self-assembly from biodegradable amine-modified poly(vinyl alcohol)-graft-poly(L-lactide): bioavailability and nasal tolerability in rats.

Authors:  Michael Simon; Matthias Wittmar; Thomas Kissel; Thomas Linn
Journal:  Pharm Res       Date:  2005-08-26       Impact factor: 4.200

  1 in total

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